{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T16:00:43Z","timestamp":1771430443606,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The measurement of the quality of life (QoL) of cystic fibrosis (CF) children in the Arabic world is of substantial importance. However, the relative lack of disease\u2010specific Arabic QoL questionnaires may represent a major challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To develop a simple questionnaire that could be used for assessing and monitoring the level of QoL in CF children, particularly in Arabic\u2010speaking populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This was a cross\u2010sectional study involving 50 children and adolescent patients with CF and their caregivers who completed 2 self\u2010administered questionnaires on health\u2010related quality of life (HRQOL); the Arabic simplified CF Questionnaire\u2010Child version for children aged more than 8 years, and the Parent version for children aged from 2 to 8 years. The psychometric properties of the questionnaires were evaluated. Children's data and clinical severity scoring were also collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The CF QoL questionnaires (child and parent versions) exhibited good internal consistency and reliability, with Cronbach's\n                      <jats:italic>\u03b1<\/jats:italic>\n                      values being (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.91, 0.871). Item\u2010item and item\u2010total correlation analyses showed adequate construct validity (0.31\u20130.86) and (0.277\u20130.682). Furthermore, patients aged 2\u20138 years scored significantly better than those aged more than 8 years for the total HRQOL score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The simplified CF QoL questionnaires are reliable and valid measures of HRQOL for CF children, especially in Arabic\u2010speaking populations. The younger children with CF showed satisfactory health\u2010related QoL levels compared to the older ones. These findings support the important role of a careful psychological assessment of CF children as a part of monitoring the disease progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71332","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T07:10:16Z","timestamp":1761203416000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a Simplified Arabic Questionnaire of Health\u2010Related Quality of Life for Children With Cystic Fibrosis"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5099-2181","authenticated-orcid":false,"given":"Heba A.","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Pulmonology Division, Faculty of Medicine Ain Shams University Children's Hospital Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neven S.","family":"Baiome","sequence":"additional","affiliation":[{"name":"Department of Educational Psychology, Faculty of Education Ain Shams University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin A.","family":"Salem","sequence":"additional","affiliation":[{"name":"Department of Educational Psychology, Faculty of Education Ain Shams University Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19127133"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2017.11.013"},{"issue":"6","key":"e_1_2_11_4_1","first-page":"5121","article-title":"The Metabolic and Molecular Basis of Inherited Disease","volume":"273","author":"Welsh M. 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