{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:07:11Z","timestamp":1790345231421,"version":"4.1.0"},"reference-count":69,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cystic fibrosis (CF) presents significant challenges for both patients and their families. However, the mental health needs of persons with cystic fibrosis (PWCF) in low\u2010 and middle\u2010income countries (LMICs) remain under\u2010explored. Limited resources, fragmented healthcare systems, and inequities in access to essential CF treatments often compound psychological stressors such as depression, anxiety, and caregiver burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This review examined existing literature, found in several medical databases (e.g., PubMed, PsychInfo, Embase, Cochrane Library), on the mental health and psychosocial challenges of PWCF and their families in LMICs. It highlights the intersection between inadequate physical healthcare and poor mental health outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Findings suggested that disparities in access to diagnostic services, medications, and multidisciplinary care exacerbate emotional distress, leading to poorer quality of life compared to their counterparts in high\u2010income countries. Families often experience financial strain, social isolation, and limited psychosocial support, which further magnify mental health challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Addressing these inequities requires integrating mental health care into routine CF management, even in resource\u2010limited settings. Low\u2010cost strategies such as regular mental health screening, translating available CF\u2010specific mental health resources, and the provision of brief interventions via digital and internet\u2010based technologies show promise for sustainable implementation. This review underscores the need for increased research in LMIC contexts and the development of scalable interventions that address both physical and psychological dimensions of CF. Ensuring parity with high\u2010income countries demands recognition of mental health as a core component of CF care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71549","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T10:20:10Z","timestamp":1773138010000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advancing Mental Healthcare for Individuals With Cystic Fibrosis in Low\u2010 and Middle\u2010Income Countries"],"prefix":"10.1002","volume":"61","author":[{"given":"Alexandra L.","family":"Quittner","sequence":"first","affiliation":[{"name":"Joe DiMaggio Cystic Fibrosis Pulmonary and Sleep Center Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Graziano","sequence":"additional","affiliation":[{"name":"Psychology Unit, Child &amp; Adolescent Psychiatry Unit Bambino Ges\u00f9 Children's Hospital, IRCCS Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7910-3210","authenticated-orcid":false,"given":"Minu P.","family":"Mohan","sequence":"additional","affiliation":[{"name":"Jacobs School of Medicine and Biomedical Sciences Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth A.","family":"Smith","sequence":"additional","affiliation":[{"name":"Jacobs School of Medicine and Biomedical Sciences Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.32607\/actanaturae.11708"},{"key":"e_1_2_9_3_1","article-title":"In Press. 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