{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T12:11:51Z","timestamp":1780315911579,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T00:00:00Z","timestamp":1775433600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cystic fibrosis (CF) is a complex genetic disorder characterized by significant clinical heterogeneity. We aimed to investigate the genotype\u2010phenotype relationship of nasal polyps (NP) in CF Registry of Turkey (CFRT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included all children registered in the CFRT in 2023, divided into two groups based on NP presentation. Clinical and demographic data were compared. The Sinus\u2010Nasal Quality of Life (QoL) Survey\u20105(SN\u20105) evaluated patients with NP history.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 2258 patients were registered, with 115 (5.1%) having NP and 2143 without NP. Age was higher in the NP group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The first and second sweat tests were higher in the NP group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Median FEV1% was 89 (31\u2013133) for the NP group and 85 (15\u2013142) for those without NP (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015). Chronic colonization of MSSA and MRSA, CF\u2010related liver disease, and CF\u2010related diabetes were also more common in NP (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). No differences were detected in pulmonary exacerbations (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). In the NP group, severe genotype and F508del were more frequent (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Elexacaftor\/tezacaftor\/ivacaftor use was more common in NP (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). A weak negative correlation was found between age and the SN\u20105 score (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020,\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.231), as well as\u00a0a weak positive correlation between age and the Visual Analog Scale (VAS) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001,\n                      <jats:italic>r\u2009<\/jats:italic>\n                      =\u20090.322).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although uncommon, NP is associated with more severe clinical and genetic characteristics in CF. These findings underscore the importance of integrating upper airway evaluation into CF management and highlight the potential for age\u2010related adaptation or improved symptom perception in older patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71608","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:36:17Z","timestamp":1775471777000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Evaluation of the Genotype and Phenotype Relationship in Patients With Nasal Polyps in Cystic Fibrosis Registry of Turkey"],"prefix":"10.1002","volume":"61","author":[{"given":"Handan","family":"Keke\u00e7","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7284-4999","authenticated-orcid":false,"given":"Tu\u011fba \u015ei\u015fmanlar","family":"Ey\u00fcbo\u011flu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Tana","family":"Aslan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2544-5781","authenticated-orcid":false,"given":"Volkan","family":"Medeni","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Public Health Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Yal\u00e7\u0131n","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1126-5965","authenticated-orcid":false,"given":"\u00d6mer Faruk","family":"\u0130pek","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3475-9950","authenticated-orcid":false,"given":"Tug\u00e7e","family":"Kantemir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar Ece","family":"Tokdemir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Necmettin Erbakan University Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma Nur","family":"Ayman","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Necmettin Erbakan University Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Figen","family":"G\u00fclen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Ege University \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atacan","family":"Ogutcu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Ege University \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdurrahman Erdem","family":"Ba\u015faran","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Akdeniz University Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fen","family":"Bingol","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Akdeniz University Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3686-2927","authenticated-orcid":false,"given":"Nazan","family":"Cobanoglu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Ankara University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yakup","family":"Can\u0131tez","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology Uludag University Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1161-5145","authenticated-orcid":false,"given":"Cansu","family":"Alt\u0131nta\u015f","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Gastroenterology \u0130stinye University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doruk","family":"Gul","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatrics \u0130stinye University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze Akca","family":"Dinc","sequence":"additional","affiliation":[{"name":"Bilkent City Hospital Pediatric Pulmonology Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beste","family":"\u00d6zsezen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Dokuz Eyl\u00fcl University \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba Ramasl\u0131","family":"G\u00fcrsoy","sequence":"additional","affiliation":[{"name":"Van Research and Training Hospital Pediatric Pulmonology Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Mersin City Hospital Pediatric Pulmonology Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demet Polat","family":"Yulu\u011f","sequence":"additional","affiliation":[{"name":"Mersin City Hospital, Pulmonology Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koray","family":"Harmanc\u0131","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology Osmangazi University Eskisehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Y\u00fcksel","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology Celal Bayar University Manisa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclben \u00d6zg\u00fcl","family":"Postuk","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Infection Disease Karadeniz Teknik University Trabzon Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melih","family":"Hangul","sequence":"additional","affiliation":[{"name":"Adana City Hospital Pediatric Pulmonology Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdi \u00c7a\u011fr\u0131","family":"Da\u011fdelen","sequence":"additional","affiliation":[{"name":"Adana City Hospital, Pediatrics Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9575-3982","authenticated-orcid":false,"given":"Pelin","family":"Asfuro\u011flu","sequence":"additional","affiliation":[{"name":"Gaziantep City Hospital Pediatric Pulmonology Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology F\u0131rat University Elaz\u0131g Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Velat","family":"\u015een","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Dicle University Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice Selimo\u011flu","family":"\u015een","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pulmonology Dicle University Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suat","family":"Sava\u015f","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Dicle University Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Ayz\u0131t","family":"K\u0131l\u0131n\u00e7","sequence":"additional","affiliation":[{"name":"Cerrahpasa Faculty of Medicine, Pediatric Pulmonology \u0130stanbul University Cerrahpasa \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ci\u011fdem","family":"Korkmaz","sequence":"additional","affiliation":[{"name":"Cerrahpasa Faculty of Medicine, Pediatric Pulmonology \u0130stanbul University Cerrahpasa \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5649-8045","authenticated-orcid":false,"given":"Berrak","family":"Oztosun","sequence":"additional","affiliation":[{"name":"Cerrahpasa Faculty of Medicine, Pediatric Pulmonology \u0130stanbul University Cerrahpasa \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"K\u00f6se","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Erciyes University Kayseri Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ersoy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Erciyes University Kayseri Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Keskin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology Gaziantep University Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaye","family":"\u0130nal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology Gaziantep University Gaziantep Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derya Ufuk","family":"Alt\u0131nta\u015f","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology \u00c7ukurova University Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6422-2639","authenticated-orcid":false,"given":"Mahir","family":"Serbes","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Allergy and Immunology \u00c7ukurova University Adana Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6n\u00fcl","family":"Caltepe","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Gastroenterology Ondokuz May\u0131s University Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"Topal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pediatric Allergy and Immunology Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"H\u0131zal","sequence":"additional","affiliation":[{"name":"Ankara Research and Training Hospital Pediatric Pulmonology Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyl\u00fcl P\u0131nar","family":"\u00c7ak\u0131r","sequence":"additional","affiliation":[{"name":"Bursa Research and Training Hospital Pediatric Pulmonology Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilay Ba\u015f","family":"\u0130kizo\u011flu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology \u0130stanbul University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halime Nay\u0131r","family":"B\u00fcy\u00fcksahin","sequence":"additional","affiliation":[{"name":"Mardin Research and Training Hospital Pediatric Pulmonology Mardin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2146-9284","authenticated-orcid":false,"given":"Faz\u0131lcan","family":"Zirek","sequence":"additional","affiliation":[{"name":"Samsun City Hospital Pediatric Pulmonology Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ece","family":"Ocak","sequence":"additional","affiliation":[{"name":"\u0130zmir City Hospital, Pediatric Pulmonology \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagehan","family":"Emiralio\u011flu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fczin","family":"Cinel","sequence":"additional","affiliation":[{"name":"Bilkent City Hospital Pediatric Pulmonology Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevgi","family":"Pekcan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Necmettin Erbakan University Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erkan","family":"\u00c7ak\u0131r","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology \u0130stinye University \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U\u011fur","family":"\u00d6z\u00e7elik","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Do\u011fru","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Pediatric Pulmonology Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23555"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22043"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132015000100009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.11.1245"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.27493"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2013.10.011"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2018.02.006"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/arm92040026"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.09.014"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.14744\/nci.2021.94547"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-023-07833-0"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2016.09.005"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2022.02.006"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2000.00241.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-012-0250-y"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino10.225"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.1.40"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202108-1986OC"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2023.03.002"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23555"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-019-0853-7"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-022-00839-x"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.06.013"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10061362"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.71608","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.71608","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.71608","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T11:32:42Z","timestamp":1780313562000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.71608"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/ppul.71608"],"URL":"https:\/\/doi.org\/10.1002\/ppul.71608","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-07-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71608"}}