{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:02:05Z","timestamp":1784728925366,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>As survival improves for individuals with cystic fibrosis (CF) worldwide, the number of adolescents requiring transition from pediatric to adult care is rapidly growing. In addition to limited resources and lack of uniform access to medical care, traditional treatments, and advanced therapies, the increasing number of transitioning young adults in low\u2010 and middle\u2010income countries (LMICs) face barriers and challenges to safe transition from pediatric to adult healthcare that are both universal and unique. This shift in demographics presents distinct challenges due to an underdeveloped and under\u2010resourced adult CF care infrastructure, sociopolitical variation, and cultural complexities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a structured literature to identify and synthesize published evidence on healthcare transition (HCT) for people with CF (pwCF) in LMICs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This manuscript summarizes available literature and insights on HCT for pwCF in LMICs, identifies key barriers, and explores cultural, religious, and health system factors. Additionally, we emphasize the practical need to transition adolescents to adult care to maintain pediatric hospital capacity for younger children, as well as the developmental and educational needs of young adults entering a medical system that is challenging for adults even without chronic disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>With much of the transition literature reflecting health systems in high\u2010income countries (HIC), this integrated socio\u2010ecological and socio\u2010cultural overview underscores the urgent need for context\u2010specific, culturally sensitive transition frameworks focused on reproductive and mental health, the integration of adolescent\u2010responsive, family\u2010inclusive, and even faith\u2010informed care models in LMICs. Our review and observations informed the author's recommendations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71645","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:08:26Z","timestamp":1779260906000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cystic Fibrosis Transition From Pediatrics to Adult Care in Low\u2010Middle Income Countries"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2335-4242","authenticated-orcid":false,"given":"Ahmet","family":"Uluer","sequence":"first","affiliation":[{"name":"Department of Pediatrics Division of Pulmonary Medicine, Boston Children's Hospital Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Internal Medicine, Division of Pulmonary and Critical Care, Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6326-3543","authenticated-orcid":false,"given":"Leah","family":"Ratner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi","family":"Asfour","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The University of Utah Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor","family":"Elshaar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pulmonary Medicine, Boston Children's Hospital Harvard Medical School Boston Massachusetts USA"},{"name":"Department of Internal Medicine, Division of Pulmonary and Critical Care, Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandra","family":"Swanson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pulmonary Medicine, Boston Children's Hospital Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"\u201c2024 Cystic Fibrosis Foundation Patient Registry Highlights \u201d Cystic Fibrosis Foundation Bethesda (MD) 2025."},{"key":"e_1_2_9_3_1","unstructured":"\u201c2023 UK Cystic Fibrosis Registry Annual Data Report \u201d Cystic Fibrosis Trust London (UK) 2024."},{"key":"e_1_2_9_4_1","unstructured":"\u201c2023 Australian Cystic Fibrosis Data Registry Annual Report Report\u202fNo\u202f25 \u201d Cystic Fibrosis Australia School of Public Health and Preventive Medicine Monash University \u202fMelbourne (Australia) 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