{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:01:59Z","timestamp":1784728919826,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"publisher","award":["BOAS23D0"],"award-info":[{"award-number":["BOAS23D0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["T32\u2010HG009495"],"award-info":[{"award-number":["T32\u2010HG009495"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["NCT04098445"],"award-info":[{"award-number":["NCT04098445"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Respiratory oscillometry (OSC) is a pulmonary function test that measures respiratory system impedance and is well\u2010suited for young children. Previous studies have suggested that there may be differences between impedance values obtained on different instruments, however, no studies comparing instruments have been done in healthy children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed both impulse oscillometry (IOS) and airwave oscillometry (AOS), in random order in a cohort of healthy children with no history of cardiopulmonary disease or recent illness. We used linear regression analysis and Bland\u2010Altman plots to compare results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty children ages 4\u201318 years completed study visits. Compared with AOS, the IOS mean and median values for resistance at 5\u2009Hz (R5) were higher (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), reactance at 5\u2009Hz (X5) mean and median values were less negative (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and both the area under the reactance curve (AX) and resonant frequency (Fres) were lower (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Bland\u2010Altman analysis revealed proportional bias between the two systems.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results in healthy children show differences between the results obtained on different OSC instruments. This may be due to differences in the type of pressure signal produced by the instrument. Our results suggest that normal values obtained on one instrument may not be comparable to results obtained on another.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71665","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T12:10:04Z","timestamp":1779711004000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Discrepancy Between Airwave and Impulse Oscillometry Measurements of Impedance in Healthy Children"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1874-303X","authenticated-orcid":false,"given":"Heather","family":"Boas","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"},{"name":"Department of Pediatrics University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2115-5944","authenticated-orcid":false,"given":"Katharine","family":"Tsukahara","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonary and Sleep Medicine University of Utah Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"McDonough","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"},{"name":"Department of Pediatrics University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tryce","family":"Scully","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Management Core Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Qiu","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Management Core Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Travaglini","sequence":"additional","affiliation":[{"name":"Division of Neonatology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Ziolkowski","sequence":"additional","affiliation":[{"name":"Division of Neonatology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Parenti","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine Children's Hospital of Philadelphia Philadelphia Pennsylvania USA"},{"name":"Department of Pediatrics 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