{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T05:19:38Z","timestamp":1788239978386,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The emergence of new disease\u2010modifying treatments for type I spinal muscular atrophy (SMA I) has led to a paradigm shift in the respiratory management of these patients. Accompanying pulmonary and thoracic growth appears to be a key factor in their morbidity and mortality. The role of Intermittent Positive Pressure Breathing (IPPB) on thoracic growth has been described in the literature, but there are few studies available to objectively assess its impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Objective<\/jats:title>\n                    <jats:p>To assess the impact of using IPPB on thoracic growth in children with SMA I.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material\/Method<\/jats:title>\n                    <jats:p>In this bicentric retrospective study, the thoracic circumference\u2010to\u2010head circumference ratio (TC\/HC) was compared at three time points: 4 months before the initiation of IPPB, at the start of IPPB, and 4 months after initiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seven children (3 girls and 4 boys) with SMA I with a median (min\u2013max) age of 4.8 (2.6\u20138.2) years old were included in this study. A statistically significant increase was observed in the mean change in TC\/HC between the pre\u2010IPPB and post\u2010IPPB periods (\u22120.05\u2009\u00b1\u20090.03 vs. +0.06\u2009\u00b1\u20090.07,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this study, IPPB was associated with a significant increase in TC\/HC in children with SMA I. Further large\u2010scale studies are warranted to better characterize the extent and clinical significance of this effect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71804","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T08:28:02Z","timestamp":1787560082000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Intermittent Positive Pressure Breathing on Thoracic Growth in Children With Type 1 Spinal Muscular Atrophy"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3010-7860","authenticated-orcid":false,"given":"Charlotte","family":"Th\u00e9bault","sequence":"first","affiliation":[{"name":"Pediatric Physical Medicine and Functional Rehabilitation Department AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Denamur","sequence":"additional","affiliation":[{"name":"Sorbonne University, Inserm, Saint\u2010Antoine Research Centre, CRSA, AP\u2010HP, Hospital Armand Trousseau Paediatric Pulmonology Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Thomas","sequence":"additional","affiliation":[{"name":"Pediatric department CHU Brest Brest France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Barzic","sequence":"additional","affiliation":[{"name":"Pediatric department CHU Brest Brest France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Pediatric Physical Medicine and Functional Rehabilitation Department AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00eblle","family":"Dupuis","sequence":"additional","affiliation":[{"name":"Pediatric Physical Medicine and Functional Rehabilitation Department AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Christine","family":"Nougues","sequence":"additional","affiliation":[{"name":"Pediatric Neurology Department AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Isapof","sequence":"additional","affiliation":[{"name":"Pediatric Neurology Department AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5765-0555","authenticated-orcid":false,"given":"Guillaume","family":"Aubertin","sequence":"additional","affiliation":[{"name":"Sorbonne University, Inserm, Saint\u2010Antoine Research Centre, CRSA, AP\u2010HP, Hospital Armand Trousseau Paediatric Pulmonology Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7552-3880","authenticated-orcid":false,"given":"Jessica","family":"Taytard","sequence":"additional","affiliation":[{"name":"Pediatric Lung Function Testing and Sleep Unit AP\u2010HP, Sorbonne Universit\u00e9, Hospital Armand Trousseau Paris France"},{"name":"UMRS1158, Experimental and Clinical Respiratory Neurophysiology, INSERM Sorbonne Universit\u00e9 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60921-6"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2952K"},{"key":"e_1_2_13_4_1","unstructured":"amyotrophie_spinale_infantile_\u2010_pnds.pdf [Internet]. 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