{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:53:38Z","timestamp":1791294818986,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Otitis media and conductive hearing loss are common in patients with primary ciliary dyskinesia (PCD). We primarily aimed to assess the impact of otologic features of individuals with PCD on health\u2010related quality of life (QOL), and our secondary aims are characterization of the coexisting pulmonary and sinonasal findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Demographic data, spirometry values, a health\u2010related quality of life questionnaire for PCD patients (QOL\u2010PCD), physical examination data of sinonasal and otologic systems, the sinonasal outcome test\u201022, and audiologic tests were recorded in this cross\u2010sectional study. The pure tone audiometry, distortion product otoacoustic emission (DPOAE), tympanogram, and the Turkish matrix test (TUR\u2010matrix) evaluating speech understanding in noise were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010six patients with PCD were included in the study. The scores of the social, upper, and lower respiratory domains of the QOL\u2010PCD were significantly lower in adults than in children and adolescents (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u2009&lt;\u20090.001, 0.02, and 0.01, respectively). The hearing and the TUR\u2010matrix were pathologic in 26 (46.4%) and 36 (64.3%) cases, respectively. Patients with pathological hearing had significantly worse results in regards to the FEV\n                      <jats:sub>1<\/jats:sub>\n                      z\u2010score (\u22121.7 vs. \u22120.8,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), the TUR\u2010matrix test (20 vs. 16 cases,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), the DPOAE (25 vs. 11 cases,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and the tympanogram (26 vs. 12 cases,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) than patients with normal hearing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Sinopulmonary involvement and hearing manifestations are very common in patients with PCD, and speech understanding in noise is often impaired. These manifestations impact QOL in various areas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71810","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:43:53Z","timestamp":1787730233000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Pulmonary and Otological Manifestations in Primary Ciliary Dyskinesia and Their Effect on Quality of Life"],"prefix":"10.1002","volume":"61","author":[{"given":"Muruvvet","family":"Yanaz","sequence":"first","affiliation":[{"name":"Division of Pediatric Pulmonology Marmara University School of Medicine Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8829-3431","authenticated-orcid":false,"given":"Ela Erdem","family":"Eralp","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology Marmara University School of Medicine Istanbul 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