{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:55:00Z","timestamp":1791294900320,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Children's interstitial and diffuse lung disease (chILD) comprise a heterogeneous group of rare disorders associated with substantial morbidity and mortality. Population\u2010based epidemiological data remain scarce in low\u2010 and middle\u2010income countries, limiting health system planning and policy development. We aimed to estimate the prevalence and temporal trends of\n                      <jats:bold>chILD<\/jats:bold>\n                      in Colombia using nationwide administrative healthcare data.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a retrospective, population\u2010based study using Colombia's Registro Individual de Prestaci\u00f3n de Servicios de Salud (RIPS) from 2016 to 2024.\n                      <jats:bold>chILD<\/jats:bold>\n                      cases were identified using ICD\u201010 codes for\n                      <jats:bold>chILD<\/jats:bold>\n                      in individuals aged 0\u201318 years. Prevalence was estimated overall, by year, sex, age group, and diagnosis. Crude and WHO age\u2010standardized prevalence rates were calculated per 100,000 population. Temporal trends were assessed using Poisson regression and LOESS smoothing.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 4608\n                      <jats:bold>chILD<\/jats:bold>\n                      \u2010related healthcare encounters were identified. The average annual crude prevalence was 3.32 per 100,000 children (age\u2010standardized: 3.39 per 100,000). Prevalence was highest in infants younger than 1 year and showed a secondary increase during adolescence. No relevant sex differences were observed. A significant annual increase in reported cases was detected (IRR 1.022; 95% CI 1.011\u20131.034), with a marked decline during the COVID\u201019 pandemic. Alveolar and fibrotic interstitial lung disease categories accounted for most cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This first nationwide study provides robust real\u2010world evidence on the epidemiology of\n                      <jats:bold>chILD<\/jats:bold>\n                      in Colombia, revealing substantial healthcare utilization and distinct age\u2010related patterns. Administrative data represents a valuable complementary tool for surveillance of rare pediatric lung diseases.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71832","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T06:54:06Z","timestamp":1789368846000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence Patterns of Children's Interstitial and Diffuse Lung Disease (chILD) in Colombia, 2016\u20132024"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9665-5791","authenticated-orcid":false,"given":"Andrea Parra","family":"Buitrago","sequence":"first","affiliation":[{"name":"Departamento de Neumolog\u00eda Pedi\u00e1trica, Hospital Pablo Tob\u00f3n Uribe, Facultad de Medicina Universidad Pontificia Bolivariana Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2404-6612","authenticated-orcid":false,"given":"Jefferson Antonio","family":"Buend\u00eda","sequence":"additional","affiliation":[{"name":"Departamento de Farmacolog\u00eda y Toxicolog\u00eda, Facultad de Medicina, Grupo de Investigaci\u00f3n en Farmacolog\u00eda y Toxicolog\u00eda Universidad de Antioquia Medell\u00edn Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201305-0923ST"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-015-0339-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207349"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1780"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000000471"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2018.03.002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10125"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-4-26"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2023-221325"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2021.06.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.26568"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-017-0637-x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-8-24"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00703-2018"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-019-1270-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-016-0389-z"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00964-2020"},{"key":"e_1_2_9_19_1","unstructured":"Restrepo\u2010Gualteros SM. 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