{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:53:58Z","timestamp":1791294838584,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the literature is limited, volume\u2010targeted pressure support (VT\u2010PS) ventilation has increasingly been used in children with tracheostomies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe a single\u2010center experience using invasive VT\u2010PS in children with tracheostomies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Ventilator Care Program registry at Children's Hospital Colorado was used to identify subjects who underwent tracheotomy between 2015 and 2024. Children (\u2264\u200921 years) with chronic mechanical ventilation for \u2265\u200914 consecutive days were included. Subjects were divided between the \u201cVT\u2010PS\u201d (VT\u2010PS\u2009\u2265\u200914 consecutive days or discharged on VT\u2010PS) and \u201cno VT\u2010PS\u201d (VT\u2010PS\u2009&lt;\u200914 consecutive days or discharged not on VT\u2010PS) groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      Three hundred twenty three subjects were mechanically ventilated via tracheostomy during the study period (VT\u2010PS,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009263 vs. no VT\u2010PS,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200960). In 2017, VT\u2010PS surpassed synchronized intermittent mandatory ventilation\u2010volume control (SIMV\u2010VC) as the most common mode of ventilation when transitioning to a portable ventilator. VT\u2010PS portable ventilator trials were more likely to be continued until discharge than SIMV\u2010VC trials (52% vs. 27.9%\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A transition to VT\u2010PS when previously using another mode on a portable ventilator resulted in a reduction in the patient's respiratory rate (median 33.0 [IQR 25.0\u221241.5] vs. 31.0 [22.5\u221239.0],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There was no significant difference in the cumulative incidence of ventilator liberation or decannulation between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>Our institution's use of VT\u2010PS has shown that this modality is well tolerated in most children with tracheostomies without adverse effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71835","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:43:52Z","timestamp":1789544632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of Volume\u2010Targeted Pressure Support in Children With Tracheostomies: A Single\u2010Center Experience"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-2054-8335","authenticated-orcid":false,"given":"Audrey","family":"Tilly\u2010Gratton","sequence":"first","affiliation":[{"name":"Section of Pulmonary and Sleep Medicine, Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Division of Respiratory Medicine, Department of Pediatrics CHU Sainte\u2010Justine, Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.","family":"Dawson","sequence":"additional","affiliation":[{"name":"Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy A.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3310-0422","authenticated-orcid":false,"given":"John T.","family":"Brinton","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1171-563X","authenticated-orcid":false,"given":"Christopher D.","family":"Baker","sequence":"additional","affiliation":[{"name":"Section of Pulmonary and Sleep Medicine, Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2019.101037"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/hpeds.2020-0038"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29402"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25730"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25102"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00500"},{"key":"e_1_2_10_8_1","unstructured":"Philips. 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