{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:06:01Z","timestamp":1761059161882,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","issue":"3-4","license":[{"start":{"date-parts":[[2011,2,15]],"date-time":"2011-02-15T00:00:00Z","timestamp":1297728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NCI\/SAIC","award":["23XS144A"],"award-info":[{"award-number":["23XS144A"]}]},{"DOI":"10.13039\/100000952","name":"The Paul G. 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This report makes these data publicly available in raw and processed forms, as a resource to the community. Importantly, we previously made biospecimens from this same mouse model freely available through a sample repository, so researchers can obtain samples to test biological hypotheses without the need of breeding animals and collecting biospecimens.<\/jats:p><jats:p><jats:bold>Experimental design<\/jats:bold>: Twelve datasets are available, encompassing 841 LC\u2010MS\/MS experiments (plasma and tissues) and 255 microarray analyses of multiple tissues (thymus, spleen, liver, blood cells, and breast). Cases and controls were rigorously paired to avoid bias.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>: In total, 18\u2009880 unique peptides were identified (PeptideProphet peptide error rate \u22641%), with 3884 and 1659 non\u2010redundant protein groups identified in plasma and tissue datasets, respectively. Sixty\u2010one of these protein groups overlapped between cancer plasma and cancer tissue.<\/jats:p><jats:p><jats:bold>Conclusions and clinical relevance<\/jats:bold>: These data are of use for advancing our understanding of cancer biology, for software and quality control tool development, investigations of analytical variation in MS\/MS data, and selection of proteotypic peptides for multiple reaction monitoring\u2010MS. The availability of these datasets will contribute positively to clinical proteomics.<\/jats:p>","DOI":"10.1002\/prca.201000037","type":"journal-article","created":{"date-parts":[[2011,1,5]],"date-time":"2011-01-05T08:52:26Z","timestamp":1294217546000},"page":"179-188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Proteome and transcriptome profiles of a Her2\/Neu\u2010driven mouse model of breast cancer"],"prefix":"10.1002","volume":"5","author":[{"given":"Regine M.","family":"Schoenherr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen S.","family":"Kelly\u2010Spratt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ChenWei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey 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