{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T06:19:39Z","timestamp":1770272379724,"version":"3.49.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Proteomics Clinical Apps"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>During COVID\u201019, significant changes in protein abundance can be linked with disease\u2010related processes. The mass spectrometry\u2013based proteomics of COVID\u201019\u2010related biomarkers can help with the prognosis and diagnosis of this severe disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Here, we surveyed scientific works in terms of proteomic analysis of solid tissues and non\u2010blood fluids from COVID\u201019 patients. Works published since 2022 to date have been covered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Brain, lymph nodes, heart, spleen, aorta walls, liver, adrenal gland and kidneys were investigated as solid organs\/tissues. The non\u2010blood fluids involved exhaled breath particles, airway mucus, saliva, swabs, colostrum\/milk and urine. The provided table depicts studies\/experimental platforms to analyse COVID\u201019\u2010related candidate protein biomarkers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Even eminent research input has been made in this field, continuation towards deeper findings should be made. Translation of proteomics into the clinics to help with diagnostics and therapeutical strategies, is a highly important task. The analysed candidate protein biomarkers are the perspective molecules for pending clinical decisions making and treatments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/prca.202400117","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T04:59:37Z","timestamp":1735621177000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["In Search of Candidate Protein Biomarkers Related to COVID\u201019 in Solid Tissues and Non\u2010Blood Fluids: An Update"],"prefix":"10.1002","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1618-1059","authenticated-orcid":false,"given":"Michal","family":"Alexovi\u010d","sequence":"first","affiliation":[{"name":"Department of Medical and Clinical Biophysics, Faculty of Medicine University of P.J. \u0160af\u00e1rik in Ko\u0161ice  Ko\u0161ice Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csilla","family":"Uli\u010dn\u00e1","sequence":"additional","affiliation":[{"name":"University Library, University of Pre\u0161ov  Pre\u0161ov Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hadi","family":"Tabani","sequence":"additional","affiliation":[{"name":"Complex Carbohydrate Research Center University of Georgia  Athens Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e1n","family":"Sabo","sequence":"additional","affiliation":[{"name":"Department of Medical and Clinical Biophysics, Faculty of Medicine University of P.J. \u0160af\u00e1rik in Ko\u0161ice  Ko\u0161ice 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