{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:12:32Z","timestamp":1789625552969,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T00:00:00Z","timestamp":1356566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to describe physical activity, quality of and satisfaction with life, pain, joint mobility and muscle function in adults with mild\u2010to\u2010moderate osteogenesis imperfecta (OI) to form the basis of improved clinical care and physical therapy treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A total of 40 men and women aged between 21 and 71\u2009years were identified and a prospective, cross\u2010sectional study was performed on 29 (18 women) included participants. The participants had to be able to walk and to have a diagnosis of mild\u2010to\u2010moderate OI. Self\u2010administered questionnaires and clinical examinations were used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Difficulties were found in all domains of the International Classification of Functioning, Activity and Health. Pain was reported in 25 of 29 participants and scoliosis was found in 23 participants. Difficulty to run was estimated in 18 participants. A total of 19 of 27 participants reported reaching the recommendations of 30\u2009min of moderate\u2010intensity activity preferably every day. Life satisfaction was high even though health\u2010related quality of life, assessed with the Short Form 36, was significantly lower than the Swedish norm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Impairments and activity limitations involved pain, scoliosis, contractures as well as trouble with running, heavy lifting, heavy work and sports. This study show that individuals with mild\u2010to\u2010moderate OI perceive themselves as having decreased health\u2010related quality of life and this seems to depend on decreased physical functioning. Despite that, as a group, they estimated high life satisfaction and 19 participants reported adhering to the general recommendation of 30\u2009min of moderate\u2010intensity activity preferably every day. Copyright \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pri.1546","type":"journal-article","created":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T06:50:11Z","timestamp":1356591011000},"page":"203-211","source":"Crossref","is-referenced-by-count":35,"title":["Functioning and Quality of Life in Adults with Mild\u2010to\u2010Moderate Osteogenesis Imperfecta"],"prefix":"10.1002","volume":"18","author":[{"given":"Veronica","family":"Balkefors","sequence":"first","affiliation":[{"name":"Department of Neurobiology Care Sciences and Society, Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet, Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Mattsson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Care Sciences and Society, Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ylva","family":"Pernow","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet, Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"S\u00e4\u00e4f","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet, Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199301000-00011"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-8-367"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.43.020192.001413"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"e_1_2_6_6_1","volume-title":"Rehabilitation research: principles and applications","author":"Domholdt E","year":"2005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1006\/pmed.2001.0847"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(89)90159-5"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/140381999443555"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1079\/PHN2005840","article-title":"Criterion\u2010related validity of the last 7\u2010day, short form of the International Physical Activity Questionnaire in Swedish adults","volume":"9","author":"Ekelund U","year":"2005","journal-title":"Public Health Nutrition"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(98)90426-9"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2001.23889"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2340\/1650197791238387","article-title":"Vocational rehabilitation in northern Sweden III. 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