{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:14:55Z","timestamp":1782184495149,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T00:00:00Z","timestamp":1696809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The adverse effects of chemotherapy\u2010induced diabetic peripheral neuropathy (CIDPN) are rather prevalent. There is no known pharmaceutical treatment that can stop CIDPN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study compared the effects of cold application and transcutaneous nerve stimulation (Transcutaneous electrical nerve stimulation (TENS)) on individuals who had undergone mastectomy following CIDPN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>Between Mars 2021 and September 2021, a randomised controlled experiment was carried out at physical therapy clinics at the Modern University for Technology and Information. 30 patients were randomly split into two equal groups (A and B). Both lower limbs received cold application (Group A) three times per week for 12 weeks and TENS application (Group B) three times each week for 12 weeks. The Visual Analogue Scale and nerve conduction velocity for the sural nerve were used to assess patients before and after 12 weeks of therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed that Group A significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) decreased pain intensity after treatment by 70.83% compared with Group B by 55.17%. Moreover, Group A improved significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) the sural nerve amplitude by 44.12% compared with group B which recorded 26.87%. After treatment, both pain intensity and sural nerve amplitude significantly (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) changed between Group A versus Group B.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cold application has a better effect on pain in CIDPN post mastectomy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pri.2051","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T05:37:51Z","timestamp":1696916271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effect of cold application versus transcutaneous nerve stimulation on chemotherapy induced diabetic peripheral neuropathy post mastectomy"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5678-0841","authenticated-orcid":false,"given":"Ahmed M.","family":"Elshinnawy","sequence":"first","affiliation":[{"name":"Department of Physical Therapy for Neuromuscular Disorders and Its Surgery Faculty of Physical Therapy Horus University  New Damietta Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeezy S.","family":"Eraky","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy for Internal Medicine and Elderly Faculty of Physical Therapy Modern University for Technology and Information  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Sami","family":"Abdelaziz","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy for Surgery Faculty of Physical Therapy Modern University for Technology and Information  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha A. F.","family":"Abd\u2010Elrahman","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy for Women's Health Faculty of Physical Therapy Badr University  Badr Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"e_1_2_15_2_1","first-page":"23","article-title":"Effects of cryotherapy on objective and subjective symptoms of paclitaxel\u2010induced neuropathy: 5 prospective self\u2010controlled trial","author":"Akiko H.","year":"2017","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0b013e3181c918fc"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526\u20104637.2011.01140.x"},{"key":"e_1_2_15_5_1","article-title":"Transcutaneous electrical nerve stimulation in rodent models of neuropathic pain: A meta\u2010analysis","volume":"16","author":"Jiapeng H.","year":"2022","journal-title":"Neurosci"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2010.03.021"},{"key":"e_1_2_15_7_1","article-title":"Diabetes mellitus in people with cancer","volume":"9","author":"Joharatnam N.","year":"2021","journal-title":"Diabetic Medicine"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jen.2020.02.017"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184360"},{"key":"e_1_2_15_10_1","first-page":"13","article-title":"Cold gel slippers can lessen the effects of chemotherapy","volume":"1","author":"Rapid Aid","year":"2022","journal-title":"Cancer"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.23467"}],"container-title":["Physiotherapy Research International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pri.2051","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T08:33:30Z","timestamp":1722242010000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pri.2051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,9]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/pri.2051"],"URL":"https:\/\/doi.org\/10.1002\/pri.2051","archive":["Portico"],"relation":{},"ISSN":["1358-2267","1471-2865"],"issn-type":[{"value":"1358-2267","type":"print"},{"value":"1471-2865","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,9]]},"assertion":[{"value":"2023-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2051"}}