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This advancement addresses potential biases in muscle strength examinations. Utilizing electrically evoked contractions from paralyzed muscles, enhanced by electrodiagnosis, holds promise in identifying false\u2010negative diagnoses of non\u2010responsiveness to neuromuscular electrical stimulation. This concept prompts the exploration of polyneuromyopathy arising from nonuse in paralyzed muscles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Series Presentation<\/jats:title><jats:p>To substantiate our hypothesis, we recruited nine participants for a case series aimed at elucidating the potential benefits of incorporating the stimulus electrodiagnostic test (SET) to mitigate non\u2010responsiveness during preparation for functional electrical stimulation (FES)\u2010assisted cycling. In our convenience sample (<jats:italic>n<\/jats:italic>\u00a0=\u00a05), we conducted neurological mapping based on ISNCSCI and applied SET on the quadriceps. The SET guided optimal dosimetry for evoking contractions and revealed responses similar to those observed in peripheral neuropathies, with <jats:italic>\u03b1<\/jats:italic> coefficients equal to or lower than 2.00. This observation is likely attributable to nonuse of paralyzed muscles, indicative of an ongoing polyneuropathy in individuals with chronic spinal cord injury (SCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Among the nine initially recruited subjects, seven exhibited responsiveness to neuromuscular electrical stimulation (78% responsiveness), with two participants excluded based on exclusion criteria. In the final five reported cases, all displayed <jats:italic>\u03b1<\/jats:italic> coefficient values indicating impaired neuromuscular accommodation, and one presented no <jats:italic>\u03b1<\/jats:italic> coefficient within the normal range. The inclusion of electrodiagnosis appears effective in averting non\u2010responsiveness, suggesting the presence of ongoing polyneuropathies in paralyzed muscles.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pri.2115","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T05:59:36Z","timestamp":1722923976000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Electrodiagnosis for mitigating false\u2010negative non\u2010responsiveness in electrical evoked contractions: A case series exploring probable polyneuromyopathy induced by nonuse"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1332-7075","authenticated-orcid":false,"given":"Bruno","family":"Flamarion\u2010dos\u2010Santos","sequence":"first","affiliation":[{"name":"Faculdade de Ceil\u00e2ndia (FCE) Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Reabilita\u00e7\u00e3o (PPGCR) and Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias e Tecnologias em Sa\u00fade (PPGCTS) Universidade de Bras\u00edlia (UnB)  Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6769-5359","authenticated-orcid":false,"given":"David Lobato","family":"Borges","sequence":"additional","affiliation":[{"name":"Faculdade de Ceil\u00e2ndia (FCE) Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Reabilita\u00e7\u00e3o (PPGCR) and Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias e Tecnologias em Sa\u00fade (PPGCTS) Universidade de Bras\u00edlia (UnB)  Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4879-1345","authenticated-orcid":false,"given":"Henrique Resende","family":"Martins","sequence":"additional","affiliation":[{"name":"Departamento de Engenharia El\u00e9trica Escola de Engenharia Universidade Federal de Minas Gerais (UFMG)  Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9858-9009","authenticated-orcid":false,"given":"Emerson","family":"Fachin\u2010Martins","sequence":"additional","affiliation":[{"name":"Faculdade de Ceil\u00e2ndia (FCE) Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias da Reabilita\u00e7\u00e3o (PPGCR) and Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Ci\u00eancias e Tecnologias em Sa\u00fade (PPGCTS) Universidade de Bras\u00edlia (UnB)  Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4081\/ejtm.2016.6085"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.2005.29037.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41393\u2010019\u20100350\u20109"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2019.1567890"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.756200"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/bjpt\u2010rbf.2014.0138"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743\u20100003\u201011\u201017"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2015.4374"},{"issue":"01","key":"e_1_2_10_10_1","first-page":"1","article-title":"Applied body composition assessment","volume":"2","author":"Heyward V. 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