{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:51:59Z","timestamp":1789998719009,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Purpose<\/jats:title><jats:p>Cancer is one of the most prevalent diseases in the general population, and is one of the main causes of changes in the population's illness profile. In this study, we assessed changes in the functional status and quality of life of patients in the first months of chemotherapy treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A prospective cohort study was carried out, collecting data from cancer patients seen at an outpatient clinic in the Midwest of Santa Catarina who had breast, lung, colon and rectum, prostate and head and neck cancer. Patients were assessed at four different times, the first at diagnosis and the following at 1\u2010month intervals after the previous assessment. The assessment included the sociodemographic profile, weight, Functional Independence Measure (FIM), <jats:italic>Timed Up &amp; Go<\/jats:italic> test (TUG <jats:italic>test<\/jats:italic>), Karnofsky Performance Status Scale and the EORTC Quality of Life Questionnaire. Statistical analyses were carried out using the IBM SPSS program, considering statistical significance <jats:italic>p\u00a0&lt;<\/jats:italic>\u00a00.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a sample of 145 patients, there was no statistically significant reduction in the functional independence and weight of the patients followed up despite the treatment instituted; moreover, they did not show significant changes in their mobility capacity. The Karnofsky Scale was directly impacted by tumor staging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>These results showed that patients with different tumors and staging at diagnosis, despite different degrees of disability, did not suffer significant changes in quality of life and self\u2010sufficiency in the first 4\u00a0months of treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pri.70026","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T23:56:32Z","timestamp":1736639792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Chemotherapy Treatment on the Functionality and Quality of Life of Cancer Patients"],"prefix":"10.1002","volume":"30","author":[{"given":"Isabela","family":"Zancanaro","sequence":"first","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandra","family":"Ceron","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Broll","family":"Zanini","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela Paula Pegoraro","family":"Bottega","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique Manfron","family":"Spanholi","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloma Kohl","family":"de Andrades","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1708-9921","authenticated-orcid":false,"given":"Antuani Rafael","family":"Baptistella","sequence":"additional","affiliation":[{"name":"Universidade do Oeste de Santa Catarina  Joa\u00e7aba Brasil"},{"name":"Hospital Universit\u00e1rio Santa Terezinha  Joa\u00e7aba Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104\u2010019\u20104390\u20101"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijc.ijc_47_18"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/medsci11020042"},{"key":"e_1_2_12_5_1","first-page":"95","volume-title":"Normas e Manuais T\u00e9cnicos Cadernos de Aten\u00e7\u00e3o Prim\u00e1ria","author":"Minist\u00e9rio da Sa\u00fade, Brasi","year":"2010"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_12_7_1","first-page":"3","volume-title":"Tratado de Oncologia","author":"Chammas R.","year":"2012"},{"key":"e_1_2_12_8_1","volume-title":"Enfermagem Oncol\u00f3gica: Conceitos e Pr\u00e1ticas","author":"Figueiredo N. 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