{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:06:21Z","timestamp":1753869981139,"version":"3.41.2"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T00:00:00Z","timestamp":1739750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Purpose<\/jats:title><jats:p>Heart failure (HF) is a complex syndrome that impacts persons\u2019 daily activities and adherence to exercise programs. Non\u2010Invasive ventilation (NIV) reduces respiratory load and improves cardiac function, potentially serving as an important adjunct in its treatment. These effects can be enhanced with a cardiac rehabilitation program, improving dyspnea and functionality. This study aimed to evaluate the effects of NIV during exercise on functional performance outcomes, dyspnea, QL, hemodynamics, and respiratory function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review followed by meta\u2010analysis was conducted. Searches were performed in PubMed, CENTRAL, Embase, LILACS, SciELO, and CINAHL. Eligibility criteria: Randomized clinical trials of patients over 18\u00a0years of age with HF, compared to a control group, were included with the objective of improving exercise tolerance. The studies were categorized as short\u2010term effects of NIV and those implementing an exercise program.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven studies were included in the qualitative review and five in the meta\u2010analysis. Only two studies presented a low risk of bias. The analyzed outcomes were the 6\u2010min walk test (6MWT), dyspnea, SpO2, heart rate (HR), systolic, and diastolic arterial pressure (SAP and DAP, respectively), maximal inspiratory and expiratory muscle strength (MIP and MEP, respectively), forced expiratory volume in one second (FEV1), and quality of life (QL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>There was a significant difference in favor of the NIV group compared to the control group in both modalities in relation to the 6MWT, with a mean difference (MD) 41.72 (CI 95% 2.15, 81.29) meters in the exercise program and MD 68.61 (CI 95% 5.69, 131.54) meters in short\u2010term effect studies. There were also favorable results in the outcomes of dyspnea and FEV1 in the NIV group (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). There were no statistically significant differences in the outcomes peripheral oxygen saturation (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.11), systolic (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.76) and diastolic blood pressure (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.93), heart rate (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.19), MIP (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.49), MEP (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.22) and QL (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.13).<\/jats:p><jats:p><jats:bold>Trail Registration:<\/jats:bold> PROSPERO CRD42022367746<\/jats:p><\/jats:sec>","DOI":"10.1002\/pri.70037","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T11:19:16Z","timestamp":1739791156000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Non\u2010Invasive Ventilatory Support as a Tool to Improve Exercise Tolerance in Patients With Heart Failure: A Systematic Review With Meta\u2010Analysis"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1463-6566","authenticated-orcid":false,"given":"Jessiane Bianca Pinheiro","family":"da Silva","sequence":"first","affiliation":[{"name":"Programa de Resid\u00eancia em Fisioterapia Hospitalar com \u00canfase em Terapia Intensiva  Salvador Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6922-2507","authenticated-orcid":false,"given":"Maria Carolina Ros\u00e1rio","family":"Santana","sequence":"additional","affiliation":[{"name":"Programa de Resid\u00eancia em Fisioterapia Hospitalar com \u00canfase em Terapia Intensiva  Salvador Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4673-8698","authenticated-orcid":false,"given":"Bruno Prata","family":"Martinez","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Medicina e Sa\u00fade (PPGMS) Universidade Federal da Bahia (UFBA)  Salvador Brazil"},{"name":"Departamento de Ci\u00eancias da Vida Universidade do Estado da Bahia  Salvador Brazil"},{"name":"Departamento de Fisioterapia Universidade Federal da Bahia  Salvador Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4656-750X","authenticated-orcid":false,"given":"Helder Brito","family":"Duarte","sequence":"additional","affiliation":[{"name":"Programa de Resid\u00eancia em Fisioterapia Hospitalar com \u00canfase em Terapia Intensiva  Salvador Brazil"},{"name":"Programa de P\u00f3s\u2010Gradua\u00e7\u00e3o em Medicina e Sa\u00fade (PPGMS) Universidade Federal da Bahia (UFBA)  Salvador Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"volume-title":"Efeitos da ventila\u00e7\u00e3o n\u00e3o invasiva versus treinamento muscular respirat\u00f3rio associado \u00e0 reabilita\u00e7\u00e3o cardiovascular na insufici\u00eancia card\u00edaca cr\u00f4nica (Thesis)","year":"2019","author":"Ara\u00fajo C. 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