{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:03:12Z","timestamp":1789560192116,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>Acute unilateral vestibulopathy (AUVP) impairs the vestibulo\u2010ocular reflex (VOR), leading to gaze instability and significant functional disability. Anti\u2010compensatory saccades (AcS) assessed using the Suppression Head Impulse Paradigm (SHIMP) reflect vestibulo\u2010saccadic interaction and may represent a marker of central compensation. The aim of the study was to analyze changes in AcS following structured visuo\u2010vestibular physical therapy (VVPT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ninety\u2010two patients with AUVP (mean age 59\u00a0years, 57 women and 35 men) completed an 8\u2010week VVPT program (one session per week). Assessments at baseline (T0) and post\u2010intervention (T1) included the video Head Impulse test (vHIT\u2010 HIMP and SHIMP) and the Dizziness Handicap Inventory (DHI). The primary outcome was the change in AcS amplitude. Secondary outcomes included changes in VOR gain and DHI score. Paired comparisons were performed using the Wilcoxon signed rank\u2010test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      AcS amplitude increased significantly after VVPT (median 189.5\u00b0\u2013239.0\u00b0;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). VOR gain showed a modest but significant increase (0.37\u20130.40;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), remaining within dysfunctional ranges. DHI scores decreased markedly (51\u201326;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). No significant association was found between baseline VOR gain and AcS variation (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a00.001;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.723), suggesting that baseline residual vestibular function did not explain the magnitude of the observed AcS change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>A significant increase in AcS amplitude was observed after an 8\u2010week VVPT program in people with AUVP, despite only limited improvement in VOR gain. These findings suggest that AcS may provide clinically relevant information on vestibulo\u2010saccadic adaptation during recovery after unilateral vestibular loss and may complement traditional VOR gain and patient\u2010reported outcome measures. However, given the study design, the observed changes should be interpreted with caution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pri.70274","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T22:36:59Z","timestamp":1782859019000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Anti\u2010Compensatory Saccades Changes After Visuo\u2010Vestibular Physical Therapy in People With Acute Unilateral Vestibulopathy: A Prospective Observational Study"],"prefix":"10.1002","volume":"31","author":[{"given":"Marco","family":"Boldreghini","sequence":"first","affiliation":[{"name":"Otoneurophysiology and Biomechanics of Human Movement Lab, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8095-2594","authenticated-orcid":false,"given":"Andrea","family":"Canale","sequence":"additional","affiliation":[{"name":"Otoneurophysiology and Biomechanics of Human Movement Lab, Department of Surgical Sciences University of Turin  Turin Italy"},{"name":"ENT Unit Azienda Ospedaliero Universitaria Citt\u00e0 della Salute e della Scienza di Torino  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Albera","sequence":"additional","affiliation":[{"name":"Otoneurophysiology and Biomechanics of Human Movement Lab, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Minichiello","sequence":"additional","affiliation":[{"name":"Otoneurophysiology and Biomechanics of Human Movement Lab, Department of Surgical Sciences University of Turin  Turin 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