{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:35:57Z","timestamp":1793162157688,"version":"4.5.0"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic ankle instability and chronic low back pain are highly prevalent in musculoskeletal conditions. Emerging evidence suggests that they are interconnected through shared biomechanical, neuromuscular, and neurophysiological mechanisms, where deficits in proprioception, postural control, and load distribution contribute to persistent dysfunction across the kinetic chain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study employed a narrative review with a conceptual framework, incorporating evidence from biomechanical, neuromuscular, and neurophysiological studies found through targeted database searches (PubMed, Scopus, and Google Scholar 2019\u20132025). Findings were thematically analyzed to establish connections between distal and proximal dysfunction within the kinetic chain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 23 studies were included. Overall, the evidence suggests consistent distal\u2010to\u2010proximal alterations in individuals with chronic ankle instability, including impaired ankle biomechanics, compensatory lumbopelvic movement patterns, and deficits in proprioception and neuromuscular control. Emerging findings also indicate neurophysiological adaptations affecting sensorimotor integration. Collectively, these findings suggest a potential association between chronic ankle instability and chronic low back pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Chronic ankle instability and chronic low back pain may coexist within a functionally interconnected kinetic system. Recognizing their potential interdependence supports a model of multi\u2010segmental stability and highlights the importance of combined ankle\u2013core rehabilitation strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pri.70307","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T17:06:41Z","timestamp":1785949601000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3359-1046","authenticated-orcid":false,"given":"Ehab A.","family":"Abdallah","sequence":"first","affiliation":[{"name":"Department of Orthopedic Physical Therapy Faculty of Physical Therapy Horus University  New Damietta Egypt"},{"name":"Department of Physical Therapy Faculty of Allied Medical Science Middle East University  Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5678-0841","authenticated-orcid":false,"given":"Ahmed M.","family":"Elshinnawy","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy for Neuromuscular Disorders and its Surgery Faculty of Physical Therapy Merit University  Sohag Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Diab","family":"Abdelhaleem","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Physical Therapy Faculty of Physical Therapy Cairo University  Giza Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0311480"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.6018\/sportk.526661"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43161\u2010023\u201000126\u2010x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0362119722600515"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.6018\/sportk.612281"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2023.100502"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000002282"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"265","article-title":"Peroneal Reaction Time and Dynamic Balance Following Ankle Proprioceptive\u2010Core Training","volume":"55","author":"Feger M. 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