{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T04:21:02Z","timestamp":1787718062991,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Purpose<\/jats:title>\n                    <jats:p>Intensive, high\u2010repetition practice is one of the strategies incorporated into upper\u2010limb task\u2010oriented training (UL\u2010TOT) to promote experience\u2010dependent neural plasticity after stroke. Although a target of 300 repetitions during a one\u2010hour UL\u2010TOT session is feasible, considerable variability in the practice dosage achieved across individuals has been observed. Multiple factors may influence practice dosage during UL\u2010TOT. Therefore, this exploratory secondary analysis aimed to examine factors associated with practice dosage during UL\u2010TOT in individuals with stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This secondary analysis included data from 33 individuals with subacute stroke enrolled in a randomized controlled trial. Associations between age, sex, stroke type, lesion location and volume, poststroke duration, upper\u2010limb paresis severity, spasticity severity, and depression severity (independent variables), and practice dosage (dependent variable) were analyzed using stepwise multiple linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the variables examined, upper\u2010limb paresis severity was the only factor retained in the final stepwise multiple linear regression model and was significantly associated with practice dosage within this dataset (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.804;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). The regression model was statistically significant and explained 63.4% of the variance in practice dosage (adjusted\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u00a0=\u00a00.634).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Upper\u2010limb paresis severity was the only factor significantly associated with practice dosage during therapist\u2010guided UL\u2010TOT in individuals with subacute stroke within this dataset. However, these findings should be interpreted with caution, given the small sample size and the exploratory nature of the analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pri.70316","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T10:58:36Z","timestamp":1786618716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Upper\u2010Limb Paresis Severity Is Associated With Practice Dosage During Task\u2010Oriented Training in Subacute Stroke\u2014An Exploratory Secondary Analysis"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3077-1688","authenticated-orcid":false,"given":"Subramanian","family":"Durairaj","sequence":"first","affiliation":[{"name":"Department of Physiotherapy Manipal College of Health Professions Manipal Academy of Higher Education  Manipal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9201-9419","authenticated-orcid":false,"given":"Akhila","family":"Jagadish","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Manipal College of Health Professions Manipal Academy of Higher Education  Manipal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0828-6977","authenticated-orcid":false,"given":"John M.","family":"Solomon","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Manipal College of Health Professions Manipal Academy of Higher Education  Manipal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8965-7484","authenticated-orcid":false,"given":"Mindy F.","family":"Levin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences School of Physical and Occupational Therapy, McGill University  Montreal Quebec Canada"},{"name":"Center for Interdisciplinary Research in Rehabilitation (CRIR)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017711816"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1545968310361957"},{"key":"e_1_2_12_4_1","volume-title":"Borg's Perceived Exertion and Pain Scales","author":"Borg G.","year":"1998"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1310\/tsr1603\u2010177"},{"issue":"1","key":"e_1_2_12_6_1","first-page":"29","article-title":"Motor and Sensory Deficits Following a Stroke: Relevance to a Comprehensive Evaluation","volume":"38","author":"Chan C. 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