{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:02:32Z","timestamp":1789646552564,"version":"4.0.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiotherapy Res Intl"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Complex Regional Pain Syndrome type 1 (CRPS\u2010I) following stroke has been managed by several conservative methods to date. But the efficacy of Low\u2010level laser therapy (LLLT) was never compared with the Mirror therapy (MT) in these cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim and Objective<\/jats:title>\n                    <jats:p>To compare the efficacy of LLLT versus MT in post\u2010stroke CRPS\u2010I.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This comparative interventional study (Trial registration number: CTRI\/2025\/05\/086943) was initially conducted with 47 patients with post\u2010stroke CRPS\u2010I after considering the inclusion and exclusion criteria. After obtaining informed consent, they were randomly divided into two groups. Along with kinesiotherapy in both the groups, LLLT was administered for Group 1 and MT for Group 2. Intensity of pain was measured by the Numerical Rating Scale (NRS), and the Fugl\u2010Meyer Assessment\u2010Upper Extremity (FMA\u2010UE) was used for assessing sensorimotor recovery. All the variables were measured at the baseline, 4\u00a0weeks\/visit 2, 8\u00a0weeks\/visit 3 and 12\u00a0weeks\/visit 4. A total of 44 cases (22 in each group) were analysed, as there were 3 dropouts on subsequent follow\u2010ups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Intra\u2010group analysis showed significant improvement in both the parameters during all the follow\u2010ups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). During inter group comparison, Group1 showed a significant improvement during follow\u2010up at 4\u00a0weeks in terms of both pain intensity (\n                      <jats:italic>P<\/jats:italic>\n                      <jats:sub>adj<\/jats:sub>\n                      \u00a0=\u00a00.039) and sensorimotor recovery (\n                      <jats:italic>P<\/jats:italic>\n                      <jats:sub>adj<\/jats:sub>\n                      \u00a0=\u00a00.022), but subsequent follow\u2010up visits showed no significant difference between the groups (\n                      <jats:italic>P<\/jats:italic>\n                      <jats:sub>adj<\/jats:sub>\n                      \u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LLLT demonstrated an early between\u2010group advantage over MT at 4\u00a0weeks in pain reduction and sensorimotor recovery in post\u2010stroke CRPS\u2010I. However, in the long run, no overall between\u2010group superiority was noted, as both groups achieved comparable outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>Institutional Scientific and Ethics committee (Reg. No: ECINEW\/INST\/2023\/1862) approval no: NRSMC\/IEC\/149\/2024.Trial Reg. no of this study under Clinical Trials Registry\u2014India: CTRI\/2025\/05\/086943<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pri.70349","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:15:01Z","timestamp":1789643701000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low\u2010Level Laser Therapy Versus Mirror Therapy for Post\u2010Stroke Complex Regional Pain Syndrome Type I: A Randomised Controlled Trial"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7159-4322","authenticated-orcid":false,"given":"Saumen Kumar","family":"De","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation NRS Medical College and Hospital  Kolkata West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9164-7648","authenticated-orcid":false,"given":"Ushnish","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation IPGMER &amp; SSKM Hospital  Kolkata West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6474-2719","authenticated-orcid":false,"given":"Saswato","family":"Majumdar","sequence":"additional","affiliation":[{"name":"HCAH Rehab &amp; Recovery Center  Kolkata West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"issue":"3","key":"e_1_2_14_2_1","first-page":"589","article-title":"A Comparative Study on the Effects of Mirror Therapy and Bilateral Arm Training on Hand Function of Chronic Hemiparetic Patients","volume":"17","author":"Alibakhshi H.","year":"2016","journal-title":"Koomesh"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.13048\/jkm.24003"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0902799"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac133.285"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.2340\/1650197771331"},{"key":"e_1_2_14_7_1","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/B978-1-4377-0884-4.10050-3","volume-title":"Physical Medicine and Rehabilitation","author":"Harvey R. 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