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Mol* was collaboratively developed by RCSB Protein Data Bank (RCSB PDB, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/rcsb.org\">RCSB.org<\/jats:ext-link>) and Protein Data Bank in Europe (PDBe, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/pdbe.org\">PDBe.org<\/jats:ext-link>) as an open\u2010source, web\u2010based, 3D visualization software suite for examination and analyses of biostructures. It is capable of displaying atomic coordinates and related experimental data of biomolecular structures together with a variety of annotations, facilitating basic and applied research, training, education, and information dissemination. Across <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/rcsb.org\">RCSB.org<\/jats:ext-link>, the RCSB PDB research\u2010focused web portal, Mol* has been implemented to support single\u2010mouse\u2010click atomic\u2010level visualization of biomolecules (e.g., proteins, nucleic acids, carbohydrates) with bound cofactors, small\u2010molecule ligands, ions, water molecules, or other macromolecules. <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/rcsb.org\">RCSB.org<\/jats:ext-link> Mol* can seamlessly display 3D structures from various sources, allowing structure interrogation, superimposition, and comparison. Using influenza A H5N1 virus as a topical case study of an important pathogen, we exemplify how Mol* has been embedded within various <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/rcsb.org\">RCSB.org<\/jats:ext-link> tools\u2014allowing users to view polymer sequence and structure\u2010based annotations integrated from trusted bioinformatics data resources, assess patterns and trends in groups of structures, and view structures of any size and compositional complexity. 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