{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T22:46:47Z","timestamp":1762642007393,"version":"3.37.3"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["KL2TR000143"],"award-info":[{"award-number":["KL2TR000143"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K07CA197077"],"award-info":[{"award-number":["K07CA197077"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Prostate"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>High\u2010fat dairy, particularly whole milk, in healthy men may increase risk of aggressive prostate cancer. However, data are limited regarding dairy after prostate cancer diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We conducted a prospective study among 1334 men with non\u2010metastatic prostate cancer in the Cancer of the Prostate Strategic Urologic Research Endeavor. Men answered a food frequency questionnaire in 2004\u20102005 (median 2 years after diagnosis) and were followed until 2016 for recurrence, defined as: prostate cancer death, bone metastases, biochemical recurrence, or secondary treatment. Multivariate Cox proportional hazards regression was used to calculate hazards ratios (HR) and 95% confidence intervals (CI) for associations between whole and low\u2010fat milk; total, high\u2010fat, and low\u2010fat dairy; and other dairy items and risk of recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a median follow\u2010up of 8 years, we observed 137 events. Men who consumed &gt;4 servings\/week versus 0\u20103 servings\/month of whole milk had an 73% increased risk of recurrence (HR: 1.73; 95%CI: 1.00, 2.98; <jats:italic>P<\/jats:italic>\u2010value\u2009=\u20090.04). Body mass index (BMI) modified the association (<jats:italic>P<\/jats:italic>\u2010interaction\u2009=\u20090.01). Among men with a BMI \u226527\u2009kg\/m<jats:sup>2<\/jats:sup>, &gt;4 servings\/week versus 0\u20103 servings\/month of whole milk was associated with a 3\u2010fold higher risk of recurrence (HR: 2.96; 95%CI: 1.58, 5.54; <jats:italic>P<\/jats:italic>\u2010value\u2009&lt;\u20090.001). No association was seen in men with BMI &lt;27\u2009kg\/m<jats:sup>2<\/jats:sup>. Low\u2010fat milk and other dairy foods were not associated with recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, whole milk consumption after prostate cancer diagnosis was associated with increased risk of recurrence, particularly among very overweight or obese men. Men with prostate cancer who choose to drink milk should select non\u2010fat or low\u2010fat options.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pros.23441","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T08:14:57Z","timestamp":1509956097000},"page":"32-39","source":"Crossref","is-referenced-by-count":22,"title":["Milk and other dairy foods in relation to prostate cancer recurrence: Data from the cancer of the prostate strategic urologic research endeavor (CaPSURE\u2122)"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8314-6253","authenticated-orcid":false,"given":"David","family":"Tat","sequence":"first","affiliation":[{"name":"Duke University School of Medicine Durham North Carolina"},{"name":"Department of Urology University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey A.","family":"Kenfield","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"},{"name":"Department of Epidemiology Harvard School of Public Health Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet E.","family":"Cowan","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette M.","family":"Broering","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter R.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin L.","family":"Van Blarigan","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"},{"name":"Department of Epidemiology and Biostatistics University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"June M.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Urology University of California San Francisco San Francisco California"},{"name":"Department of Epidemiology and Biostatistics University of California San Francisco San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21387"},{"key":"e_1_2_9_3_1","unstructured":"Cancer Facts & Figures 2017. 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