{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:21:03Z","timestamp":1791883263116,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T00:00:00Z","timestamp":1677974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Prostate"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS) is a heterogenous condition that impacts the Quality of life severely, and it has multimodal complex treatment options. We aimed to compare the efficacy of two well\u2010described neuromodulation therapies, transcutaneous tibial nerve stimulation (TTNS) versus percutaneous tibial nerve stimulation (PTNS) in the treatment of category IIIB CP\/CPPS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was designed as a randomized prospective clinical trial. We randomized category IIIB CP\/CPPS patients into two treatment groups as TTNS and PTNS groups. Category IIIB CP\/CPPS was diagnosed by two or four\u2010glass Meares\u2010Stamey test. All patients included in our study were antibiotic\/anti\u2010inflammatory resistant. Transcutaneous and percutaneous treatments were applied 30\u2009min sessions for 12 weeks. Patients were evaluated by Turkish\u2010validated National Health Institute Chronic Prostatitis Symptom Index (NIH\u2010CPSI) and visual analogue scale (VAS) initially and after treatment. Treatment success was evaluated within each group and also compared with each other.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 38 patients in the TTNS group and 42 patients in the PTNS group were included in the final analysis. The mean VAS scores of the TTNS group were lower than the PTNS group initially (7.11 and 7.43, respectively), (<jats:italic>p<\/jats:italic>\u2009=\u20090.03). The pretreatment NIH\u2010CPSI scores were similar between groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.07). VAS scores, total NIH\u2010CPSI, NIH\u2010CPSI micturation, NIH\u2010CPSI pain, and NIH\u2010CPSI QoL scores decreased significantly at the end of the treatment in both groups. We found a significantly higher VAS and NIH\u2010CPSI scores decrease in the PTNS group compared to the TTNS group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both PTNS and TTNS are effective treatment methods in category IIIB CP\/CPPS. Comparing the two methods, PTNS provided a higher level of improvement in terms of pain and quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pros.24513","type":"journal-article","created":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T19:14:18Z","timestamp":1678043658000},"page":"751-758","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparison of transcutaneous tibial nerve stimulation versus percutaneous tibial nerve stimulation in category IIIB chronic prostatitis\/chronic pelvic pain syndrome: A randomized prospective trial"],"prefix":"10.1002","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7571-7669","authenticated-orcid":false,"given":"Mehmet","family":"Sevim","sequence":"first","affiliation":[{"name":"Department of Urology, Faculty of Medicine Kutahya Health Sciences University  K\u00fctahya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6116-9588","authenticated-orcid":false,"given":"Okan","family":"Alki\u015f","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine Kutahya Health Sciences University  K\u00fctahya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2313-3522","authenticated-orcid":false,"given":"\u0130brahim G\u00fcven","family":"Kartal","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine Kutahya Health Sciences University  K\u00fctahya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0202-0454","authenticated-orcid":false,"given":"Huseyin Ozgur","family":"Kazan","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine Kutahya Health Sciences University  K\u00fctahya 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