{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T09:10:37Z","timestamp":1748509837261,"version":"3.37.3"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Prostate"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The uncertainty of target location during prostate cancer radiotherapy plays an important role in accurate dose delivery and radiation toxicity in adjacent organs. This study analyzed displacement correlations between the prostate and pelvic floor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Materials<\/jats:title><jats:p>We retrospectively analyzed registration results from 467 daily cone\u2010beam computed tomography (CT) in 12 patients with prostate cancer who received radiation therapy. We analyzed prostate displacement and the pelvic floor relative to the pelvic bone's anatomy in the translational and rotational directions and identified statistical correlations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The systematic (\u03a3) and random (\u03c3) displacements of the prostate in the three translational directions, anterior\u2013posterior (AP), superior\u2013inferior (SI), and right\u2013left (RL), were 1.49\u2009\u00b1\u20091.45, 2.10\u2009\u00b1\u20091.40, and 0.24\u2009\u00b1\u20090.53\u2009mm, respectively, and in the rotational directions of the pitch, roll, and yaw were 2.10\u2009\u00b1\u20092.02\u00b0, 0.42\u2009\u00b1\u20090.74\u00b0, and 0.42\u2009\u00b1\u20090.64\u00b0, respectively. The pelvic floor displacements were 2.37\u2009\u00b1\u20091.96, 2.71\u2009\u00b1\u20092.28, and 0.47\u2009\u00b1\u20090.84\u2009mm in the AP, SI, and RL directions, respectively, and 0.93\u2009\u00b1\u20091.49\u00b0, 0.98\u2009\u00b1\u20091.28 \u00b0, and 0.87\u2009\u00b1\u20090.94\u00b0 in the pitch, roll, and yaw directions, respectively. Additionally, there were statistically significant correlations between the displacement of the prostate and pelvic floor in the AP and SI directions, with correlation coefficients (<jats:italic>r<\/jats:italic>) of 0.74 (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009<jats:italic>0.001<\/jats:italic>) and 0.69 (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009<jats:italic>0.001<\/jats:italic>), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The movement of the pelvic floor may be an important factor that causes prostate displacement, affecting the accuracy of radiotherapy. Therefore, it is necessary to take appropriate measures to ensure that the pelvic floor muscle tension is as consistent as possible in the treatment\u2019 CT scan and daily treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pros.24808","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T16:44:49Z","timestamp":1728405889000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Investigation of pelvic floor influence on prostate displacement in image\u2010guided radiotherapy"],"prefix":"10.1002","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9677-3547","authenticated-orcid":false,"given":"Hongbo","family":"Chai","sequence":"first","affiliation":[{"name":"Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical Science Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuya","family":"Miyasaka","sequence":"additional","affiliation":[{"name":"Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical Science Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhito","family":"Hagiwara","sequence":"additional","affiliation":[{"name":"Department of Radiology Yamagata University Faculty of Medicine Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Souda","sequence":"additional","affiliation":[{"name":"Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical Science Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyu","family":"Ishizawa","sequence":"additional","affiliation":[{"name":"Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical Science Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiraku","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Radiology Yamagata University Faculty of Medicine Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Iwai","sequence":"additional","affiliation":[{"name":"Department of Heavy Particle Medical Science Yamagata University Graduate School of Medical Science Yamagata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1177\/153303461000900505"},{"key":"e_1_2_10_3_1","first-page":"113","volume-title":"Radiation Medicine Rounds Prostate Cancer","author":"Stenmark MH","year":"2011"},{"doi-asserted-by":"publisher","key":"e_1_2_10_4_1","DOI":"10.21037\/tau.2017.12.37"},{"doi-asserted-by":"publisher","key":"e_1_2_10_5_1","DOI":"10.1118\/1.3271389"},{"doi-asserted-by":"publisher","key":"e_1_2_10_6_1","DOI":"10.1016\/j.ijrobp.2009.06.093"},{"doi-asserted-by":"publisher","key":"e_1_2_10_7_1","DOI":"10.1118\/1.4903292"},{"doi-asserted-by":"publisher","key":"e_1_2_10_8_1","DOI":"10.1016\/0360-3016(94)00351-K"},{"doi-asserted-by":"publisher","key":"e_1_2_10_9_1","DOI":"10.1111\/j.1440-1673.1998.tb00586.x"},{"doi-asserted-by":"publisher","key":"e_1_2_10_10_1","DOI":"10.1016\/S0360-3016(98)00265-X"},{"doi-asserted-by":"publisher","key":"e_1_2_10_11_1","DOI":"10.1016\/S0360-3016(00)00751-3"},{"doi-asserted-by":"publisher","key":"e_1_2_10_12_1","DOI":"10.1016\/j.ijrobp.2003.10.017"},{"doi-asserted-by":"publisher","key":"e_1_2_10_13_1","DOI":"10.1016\/j.ijrobp.2006.03.055"},{"doi-asserted-by":"publisher","key":"e_1_2_10_14_1","DOI":"10.1186\/1748-717X-6-145"},{"doi-asserted-by":"publisher","key":"e_1_2_10_15_1","DOI":"10.1016\/j.radonc.2008.12.021"},{"doi-asserted-by":"publisher","key":"e_1_2_10_16_1","DOI":"10.1016\/0167-8140(95)01613-L"},{"doi-asserted-by":"publisher","key":"e_1_2_10_17_1","DOI":"10.1007\/s00384-013-1784-8"},{"doi-asserted-by":"publisher","key":"e_1_2_10_18_1","DOI":"10.1007\/s11764-015-0481-8"},{"doi-asserted-by":"publisher","key":"e_1_2_10_19_1","DOI":"10.1016\/j.ijrobp.2020.09.054"},{"doi-asserted-by":"publisher","key":"e_1_2_10_20_1","DOI":"10.1016\/j.ijrobp.2005.02.036"},{"doi-asserted-by":"publisher","key":"e_1_2_10_21_1","DOI":"10.1002\/nau.20144"},{"doi-asserted-by":"publisher","key":"e_1_2_10_22_1","DOI":"10.1007\/s12565-019-00521-2"},{"doi-asserted-by":"publisher","key":"e_1_2_10_23_1","DOI":"10.1016\/j.ijrobp.2005.07.973"},{"doi-asserted-by":"publisher","key":"e_1_2_10_24_1","DOI":"10.1259\/bjr.20200571"},{"doi-asserted-by":"publisher","key":"e_1_2_10_25_1","DOI":"10.1016\/j.ijrobp.2011.08.007"},{"doi-asserted-by":"publisher","key":"e_1_2_10_26_1","DOI":"10.1097\/DCR.0000000000001449"},{"doi-asserted-by":"publisher","key":"e_1_2_10_27_1","DOI":"10.1016\/S0360-3016(99)00468-X"},{"doi-asserted-by":"publisher","key":"e_1_2_10_28_1","DOI":"10.1016\/j.ijrobp.2007.05.046"},{"doi-asserted-by":"publisher","key":"e_1_2_10_29_1","DOI":"10.1016\/j.ijrobp.2005.12.033"},{"doi-asserted-by":"publisher","key":"e_1_2_10_30_1","DOI":"10.1016\/j.jpag.2018.11.010"},{"doi-asserted-by":"publisher","key":"e_1_2_10_31_1","DOI":"10.1016\/j.jvoice.2018.09.024"},{"unstructured":"BordoniB SugumarK LeslieSWAnatomy abdomen and pelvis pelvic floor.StatPearls.2020;https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482200\/(accessed on 17 November 2021)","key":"e_1_2_10_32_1"},{"issue":"23","key":"e_1_2_10_33_1","first-page":"2147","article-title":"Functional characteristics features in anatomy and physiology of the anal canal","volume":"23","author":"Teramoto Tatsuo","year":"1990","journal-title":"Nichisyougekaishi"},{"doi-asserted-by":"publisher","key":"e_1_2_10_34_1","DOI":"10.1002\/ca.23508"},{"key":"e_1_2_10_35_1","first-page":"717","article-title":"Observations on surgical anatomy for rectal cancer surgery","volume":"45","author":"Nano M","year":"1998","journal-title":"Hepato\u2010gastroenterology"},{"doi-asserted-by":"publisher","key":"e_1_2_10_36_1","DOI":"10.1016\/j.radonc.2004.12.010"},{"doi-asserted-by":"publisher","key":"e_1_2_10_37_1","DOI":"10.1016\/j.radonc.2007.09.008"},{"doi-asserted-by":"publisher","key":"e_1_2_10_38_1","DOI":"10.1007\/BF01901527"},{"doi-asserted-by":"publisher","key":"e_1_2_10_39_1","DOI":"10.1016\/j.juro.2006.06.010"},{"doi-asserted-by":"publisher","key":"e_1_2_10_40_1","DOI":"10.1016\/S1474-4422(15)00070-8"},{"doi-asserted-by":"publisher","key":"e_1_2_10_41_1","DOI":"10.1186\/s12894-019-0546-5"},{"doi-asserted-by":"publisher","key":"e_1_2_10_42_1","DOI":"10.1053\/j.gastro.2005.06.062"},{"doi-asserted-by":"publisher","key":"e_1_2_10_43_1","DOI":"10.1097\/01.psy.0000145823.85658.0c"},{"doi-asserted-by":"publisher","key":"e_1_2_10_44_1","DOI":"10.1016\/S0360-3016(99)00040-1"}],"container-title":["The Prostate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pros.24808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T11:31:18Z","timestamp":1734348678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pros.24808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,8]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/pros.24808"],"URL":"https:\/\/doi.org\/10.1002\/pros.24808","archive":["Portico"],"relation":{},"ISSN":["0270-4137","1097-0045"],"issn-type":[{"type":"print","value":"0270-4137"},{"type":"electronic","value":"1097-0045"}],"subject":[],"published":{"date-parts":[[2024,10,8]]},"assertion":[{"value":"2024-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}