{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:21:26Z","timestamp":1789435286529,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Prostate"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prostate cancer remains a significant public health issue globally, with considerable disparities in diagnostic and management practices, especially in Africa. Traditional diagnostic methods such as transrectal ultrasound\u2010guided biopsies have limitations in accuracy and are associated with potential complications. Emerging targeted biopsy techniques promise improved cancer detection rates and reduced morbidity but face adoption challenges across the African continent due to variable access to advanced imaging technologies and professional expertise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to evaluate the current practices of prostate biopsy techniques in Africa, focusing particularly on the readiness for and integration of targeted biopsy methods. It assesses the accessibility, quality, volume of procedures, and availability of advanced diagnostic tools across different regions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The survey included 58 centers across five African regions, representing a 70% response rate from an initial 83 invitations sent. Finger\u2010guided biopsy was the most common method, used by 41 centers, while only one center reported using MRI fusion biopsy. Thirty\u2010five centers routinely administered a rectal enema, and nearly all (<jats:italic>n<\/jats:italic>\u2009=\u200950) centers employed antibiotic prophylaxis, predominantly fluoroquinolones. For anesthesia, 12 centers used injectable lidocaine, and 38 centers used intrarectal lidocaine gel. The number of biopsy cores taken varied, with most centers taking 12, while others used fewer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings indicate a critical need for concerted efforts to bridge the gap in prostate cancer diagnostics and treatment in Africa. Enhancing the quality of prostate cancer care on the continent requires investments in training, infrastructure, and standardization of practices. Collaborative efforts towards adopting advanced diagnostic tools and methods are essential for aligning African practices with global standards, ultimately improving outcomes for prostate cancer patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pros.24867","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T07:43:29Z","timestamp":1738914209000},"page":"638-645","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Current Status of Prostate Biopsy in Africa: Are We Ready for a Targeted Biopsy?"],"prefix":"10.1002","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8934-8200","authenticated-orcid":false,"given":"Ziba Ouima Justin","family":"Dieudonne","sequence":"first","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University Teaching Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2270-6632","authenticated-orcid":false,"given":"Kaleab Habtemichae","family":"Gebreselassie","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"Worabe Comprehensive Specialized Hospital Worabe Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taofiq Olayinka","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"Department of Surgery Division of Urology, University of Ilorin Teaching Hospital Ilorin Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullahi","family":"Khalid","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University Teaching Hospital Usmanu Danfodiyo Sokoto Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-6350","authenticated-orcid":false,"given":"Saleh Abdelkerim","family":"Nedjim","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University Hospital La Renaissance N'djamena Chad"},{"name":"University of Adam Barka of Ab\u00e9ch\u00e9 (UNABA) Ab\u00e9ch\u00e9 Chad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5338-1589","authenticated-orcid":false,"given":"Anteneh Tadesse","family":"Kifle","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"PCEA CHOGORIA Hospital Chogoria Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella D. C.","family":"Biyouma","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"H\u00f4pital Laquintinie Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Dogo","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University of Maiduguri Teaching Hospital Maiduguri Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Agbo","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"Benue State University Teaching Hospital Makurdi Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhawenimana","family":"Emmanuel","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University Teaching Hospital of Kigali Kigali Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamat Ali","family":"Mahamat","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"University Teaching Hospital, la R\u00e9f\u00e9rence Nationale N'Djamena Chad"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndoye Alain","family":"Khassim","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"Le Dantec Hospital Dakar Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lazarus","family":"John","sequence":"additional","affiliation":[{"name":"Groote Schuur Hospital Cape Town South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yameogo Clotaire Alexis Marie Kiemdiba","family":"Donega","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Lezrek","sequence":"additional","affiliation":[{"name":"Modern Urology For Africa Casablanca Morocco"},{"name":"H\u00f4pital Militaire My Ismail Mekn\u00e8s Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirakoya","family":"Brahima","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ouattara","family":"Adama","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sourou Sanon Bobo\u2010Dioulasso Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kabore Fasnewende","family":"Aristide","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Yalgado Ouedraogo Ouagadougou Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2005.10.002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/ua.ua_128_22"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12301-021-00240-z"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2019.04.043"},{"issue":"3","key":"e_1_2_11_6_1","first-page":"93","article-title":"Prostate Biopsy: Current Status and Limitations","volume":"9","author":"Presti J. C.","year":"2007","journal-title":"Reviews in Urology"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-007-0181-8"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.06.004"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/03915603221143419"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.5152\/tud.2019.19051"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14572"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10622.x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2020.1086"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-019-0496-y"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000947"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112139-20211125-00556"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0393-2249.18.03048-5"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-020-01627-8"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12381"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11091551"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e32835ad3ee"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06654-2"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14060"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.08.018"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12301-021-00155-9"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.04.017"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-022-01006-6"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-04967-6"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.4102\/safp.v65i1.5621"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.4992"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40134-019-0336-6"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-019-1573-0"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12301-011-0016-0"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.51496\/jogm.v4.S1.215"}],"container-title":["The Prostate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pros.24867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T06:03:24Z","timestamp":1744783404000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pros.24867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,6]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/pros.24867"],"URL":"https:\/\/doi.org\/10.1002\/pros.24867","archive":["Portico"],"relation":{},"ISSN":["0270-4137","1097-0045"],"issn-type":[{"value":"0270-4137","type":"print"},{"value":"1097-0045","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,6]]},"assertion":[{"value":"2024-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}