{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T10:31:14Z","timestamp":1784716274996,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Prostate"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Rez\u016bm therapy is a minimally invasive treatment for male lower urinary tract symptoms (LUTS) related to benign prostatic obstruction (BPO), validated in selected patients through randomized trials. However, its effectiveness in broader real\u2010world populations remains underreported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective study included 110 patients treated with Rez\u016bm between 2020 and 2022. Patients were stratified according to their conformity to the original trial criteria (\u201cpilot\u201d vs. \u201cnonpilot\u201d groups). Functional outcomes, retreatment rates, sexual function and adverse events were analyzed at 24 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 24 months, both groups experienced a significant and sustained reduction in IPSS from baseline, with a median decrease of 18 points (IQR: 15\u201320) in the pilot group and 19 points (IQR: 16\u201322) in the non\u2010pilot group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.2). Improvements in IPSS\u2010QoL, Q\n                      <jats:sub>max<\/jats:sub>\n                      , and PVR were also significant and comparable between groups. Overall, 23% of patients required retreatment: 24% in the pilot group and 24% in the non\u2010pilot group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.9), including medical retreatment in 15% and 5%, and surgical retreatment in 8% and 16%, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.2). No independent predictor of retreatment was identified. Ejaculatory function was preserved in over 90% of patients at 24 months in both groups, and erectile function remained stable throughout follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Rez\u016bm therapy provides effective, durable symptom relief and preserves sexual function at 2 years, even in patients with larger prostates, prior surgery, or indwelling catheters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pros.70087","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T18:58:01Z","timestamp":1762282681000},"page":"314-319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Two\u2010Year Outcomes of Rez\u016bm Therapy in Real\u2010Life BPH Patients"],"prefix":"10.1002","volume":"86","author":[{"given":"Thibaut","family":"Long Depaquit","sequence":"first","affiliation":[{"name":"Department of Urology H\u00f4pital d\u2032Instruction des Arm\u00e9es Sainte\u2010Anne Toulon France"},{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Berchiche","sequence":"additional","affiliation":[{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Uleri","sequence":"additional","affiliation":[{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Ag\u00fcero","sequence":"additional","affiliation":[{"name":"Department of Urology H\u00f4pital d\u2032Instruction des Arm\u00e9es Sainte\u2010Anne Toulon France"},{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1158-0082","authenticated-orcid":false,"given":"Arthur","family":"Peyrottes","sequence":"additional","affiliation":[{"name":"Department of Urology, H\u00f4pital Saint\u2010Louis Assistance Publique\u2013H\u00f4pitaux de Paris (AP\u2010HP) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Corral","sequence":"additional","affiliation":[{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Baboudjian","sequence":"additional","affiliation":[{"name":"Department of Urology, H\u00f4pital Nord Assistance Publique\u2013H\u00f4pitaux de Marseille (AP\u2010HM) Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamadou","family":"Bah","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalier du Pays d\u2032Aix Aix\u2010en\u2010Provence France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fourmarier","sequence":"additional","affiliation":[{"name":"Department of Urology Centre Hospitalier du Pays d\u2032Aix Aix\u2010en\u2010Provence France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/13685538.2018.1434772"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.05.046"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2023.03.004"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2015.10.181"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2017.10.023"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-021-02899-3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05433-z"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2023.10.036"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2021.03.001"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.02.014"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2018.12.041"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.12.045"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0279883"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-024-00836-w"},{"issue":"6","key":"e_1_2_10_16_1","first-page":"1399","article-title":"Real\u2010World Early Outcomes and Retreatment Rates Following Rez\u016bm Therapy for Benign Prostatic Hyperplasia","volume":"40","author":"Whiting D.","year":"2022","journal-title":"World Journal of Urology"},{"issue":"5","key":"e_1_2_10_17_1","first-page":"485","article-title":"Outcomes of Rez\u016bm Water Vapor Therapy for Patients With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: A Real\u2010Life Experience","volume":"107","author":"Cakiroglu B.","year":"2023","journal-title":"Urologia Internationalis"},{"issue":"47","key":"e_1_2_10_18_1","article-title":"Rez\u016bm Water Vapor Thermal Therapy In Patients With Benign Prostatic Hyperplasia: A Japanese Real\u2010World Multicenter Study","volume":"102","author":"Obinata D.","year":"2023","journal-title":"Medicine 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Prostate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pros.70087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T08:51:52Z","timestamp":1768035112000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pros.70087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,4]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/pros.70087"],"URL":"https:\/\/doi.org\/10.1002\/pros.70087","archive":["Portico"],"relation":{},"ISSN":["0270-4137","1097-0045"],"issn-type":[{"value":"0270-4137","type":"print"},{"value":"1097-0045","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,4]]},"assertion":[{"value":"2025-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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