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Even worse, with the emergence and spreading of the first\u2010line drug\u2010resistant\n                    <jats:italic>Plasmodium<\/jats:italic>\n                    parasites, therapeutic interventions based on novel plasmodial drug targets are more necessary than ever. Given that the blood\u2010stage parasites primarily rely on glycolysis for their energy supply, blocking glucose uptake, the rate\u2010limiting step of ATP generation, was considered a promising approach to kill these parasites. To achieve this goal, characterization of the plasmodial hexose transporter and development of selective inhibitors have been pursued for decades. Here, we review the identification and characterization of the\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    hexose transporter (PfHT1) and summarize current advances in its inhibitor development.\n                  <\/jats:p>","DOI":"10.1002\/prot.26351","type":"journal-article","created":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T04:34:28Z","timestamp":1650515668000},"page":"1766-1778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["An overview of the\n                    <scp>\n                      <i>Plasmodium falciparum<\/i>\n                    <\/scp>\n                    hexose transporter and its therapeutic interventions"],"prefix":"10.1002","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7288-8278","authenticated-orcid":false,"given":"Xin","family":"Jiang","sequence":"first","affiliation":[{"name":"School of Biotechnology and 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