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The cysteines oxidize in air to give the same disulfide pairings as seen in the parent toxins as the major product. The three\u2010dimensional structure of the core sequence peptide, termed Max, was determined using proton NMR spectroscopy and found to be identical in secondary structure to the toxins. However differences were found in the relative orientation of the \u03b2\u2010hairpin and helix. The use of this structural motif, found in many insect toxins, as a disulfide framework for exploring sequence\/structure\/activity relationships is discussed. \u00a9 1994 John Wiley &amp; Sons, Inc.<\/jats:p>","DOI":"10.1002\/prot.340180302","type":"journal-article","created":{"date-parts":[[2005,5,29]],"date-time":"2005-05-29T01:31:51Z","timestamp":1117330311000},"page":"205-215","source":"Crossref","is-referenced-by-count":8,"title":["Solution structure of a core peptide derived from scyllatoxin"],"prefix":"10.1002","volume":"18","author":[{"given":"Mark D.","family":"Pagel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Wemmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0301-4622(88)80015-2"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00431a034"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1720574"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1991.tb15780.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.20.7443"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.11.6496"},{"key":"e_1_2_1_8_2","unstructured":"Entry 1SN3 version Jan.1992."},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(77)80200-3"},{"key":"e_1_2_1_10_2","first-page":"107","volume-title":"Crystallographic Databases.","author":"Abola E. 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