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In the process of the brain converting light into visual signals, the eye is stimulated by harmful blue\u2010light radiation directly. Thus, the eye is especially vulnerable to oxidative stress and becomes one of the organs most seriously involved during the aging process. Cataracts, age\u2010related macular degeneration (AMD), glaucoma, diabetic retinopathy (DR), and dry eye are inextricably linked to the aging process and oxidative stress. Chlorogenic acid (CGA) has been demonstrated to have antioxidant and anti\u2010inflammatory activities, and its validity has been established experimentally in numerous fields, including cardiovascular disease, metabolic disorders, cancers, and other chronic diseases. There has previously been evidence of CGA's therapeutic effect in the field of ophthalmopathy. Considering that many ophthalmic drugs lead to systemic side effects, CGA may act as a natural exogenous antioxidant for patients to take regularly, controlling their condition while minimizing side effects. In this paper, in\u00a0vitro and in\u00a0vivo studies of CGA in the treatment of age\u2010related eye diseases are reviewed, and the prospects of CGA's antioxidant application for the eye are discussed. The aim of this review is to summarize the relevant knowledge and provide theoretical support for future research.<\/jats:p>","DOI":"10.1002\/prp2.1162","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T04:53:51Z","timestamp":1704689631000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Antioxidant potential of chlorogenic acid in\n                    <scp>Age\u2010Related<\/scp>\n                    eye diseases"],"prefix":"10.1002","volume":"12","author":[{"given":"Yu","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology The First Hospital of Hunan University of Chinese Medicine  Changsha China"},{"name":"Hunan University of Chinese Medicine  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Scientific Research The First Hospital 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