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A cross\u2010sectional analysis was undertaken using MedicineInsight, a national database of de\u2010identified general practice electronic health records. We estimated the proportion of patients (per 1000, \u2030) in 2017 receiving concurrent prescriptions for opioid and BZD medications for long\u2010term use (\u2265\u20093 prescriptions within 90\u2009days). Poisson regression models were used to estimate the marginal adjusted prevalence (<jats:sub>adj<\/jats:sub>P) and adjusted prevalence ratios (<jats:sub>adj<\/jats:sub>PR) were used to compare concurrent long\u2010term prescribing according to sociodemographic characteristics, rurality, smoking status, and diagnosis of mental health or musculoskeletal conditions. The sample included 1,207,671 individuals (41.3% males; mean age 50.6\u2009\u00b1\u200918.6\u2009years) regularly attending 544 general practices. The prevalence of concurrent long\u2010term opioid and BZD prescribing was 7.0\u2030, and the median duration of prescribing overlap was 611\u2009days (p25\u2010p75 348\u2013952). The prevalence was higher for patients aged over 65\u2009years (<jats:sub>adj<\/jats:sub>PR\u2009=\u20093.62 95% CI 3.30, 3.98), females (<jats:sub>adj<\/jats:sub>PR\u2009=\u20091.33 95% CI 1.27, 1.39), those living in more disadvantaged (<jats:sub>adj<\/jats:sub>PR\u2009=\u20091.70 95% CI 1.49, 1.93) or rural\/remote areas (<jats:sub>adj<\/jats:sub>PR\u2009=\u20091.13 95% CI 1.00, 1.28), smokers (<jats:sub>adj<\/jats:sub>PR\u2009=\u20094.10 95% CI 3.87, 4.35), and those with mental health (<jats:sub>adj<\/jats:sub>PR\u2009=\u20093.23; 95% CI 2.83, 3.69) or musculoskeletal conditions (<jats:sub>adj<\/jats:sub>PR\u2009=\u20092.74; 95% CI 2.47, 3.04). In patients with both mental health and musculoskeletal conditions, the prevalence was 32.1\u2030. Interventions to reduce concurrent long\u2010term prescribing could be targeted to the identified vulnerable groups.<\/jats:p>","DOI":"10.1002\/prp2.70084","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T06:14:37Z","timestamp":1745993677000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Concurrent Prescribing of Opioids and Sedative\u2010Hypnotic Drugs for Long\u2010Term Use in Australian General Practice: A Cross\u2010Sectional Analysis Using <scp>MedicineInsight<\/scp>"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7721-4152","authenticated-orcid":false,"given":"Susan","family":"Williams","sequence":"first","affiliation":[{"name":"Adelaide Rural Clinical School, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josie","family":"Rositano","sequence":"additional","affiliation":[{"name":"Adelaide Rural Clinical School, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Haeusler","sequence":"additional","affiliation":[{"name":"Adelaide Rural Clinical School, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghana","family":"Bhat","sequence":"additional","affiliation":[{"name":"ANU College of Health and Medicine The Australian National University  Canberra Australian Capital Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberley","family":"Omond","sequence":"additional","affiliation":[{"name":"Discipline of General Practice, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Stocks","sequence":"additional","affiliation":[{"name":"Discipline of General Practice, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7153-2878","authenticated-orcid":false,"given":"David","family":"Gonzalez\u2010Chica","sequence":"additional","affiliation":[{"name":"Adelaide Rural Clinical School and Discipline of General Practice, Faculty of Health and Medical Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20102667(22)00013\u20105"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsad124"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2023.100557"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2019.02.033"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6626a4"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k3207"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(18)30471\u20101"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1337"},{"issue":"43","key":"e_1_2_14_10_1","first-page":"1487","article-title":"Vital Signs: Overdoses of Prescription Opioid Pain Relievers \u2010 United States, 1999\u20102008","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","journal-title":"MMWR. 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