{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T21:42:21Z","timestamp":1781905341586,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Res & Perspec"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1002\/prp2.70138","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T06:40:08Z","timestamp":1750142408000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Bridging Clinical Outcomes and Cost\u2010Effectiveness: The Role of Real\u2010World Data in Cystic Fibrosis Therapy"],"prefix":"10.1002","volume":"13","author":[{"given":"Ida","family":"\u0160timac","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Rijeka  Rijeka Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Katrin","family":"Faour","sequence":"additional","affiliation":[{"name":"Independent Researcher  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira Meni Maria","family":"Gkrinia","sequence":"additional","affiliation":[{"name":"Independent Researcher  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrej","family":"Belan\u010di\u0107","sequence":"additional","affiliation":[{"name":"Department of Basic and Clinical Pharmacology and Toxicology Faculty of Medicine, University of Rijeka  Rijeka Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.70083"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.16140"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckad160.1147"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273\u2010017\u20100500\u2010x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3325\/cmj.2024.65.454"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/picr.picr_62_21"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bcp.70013"},{"key":"e_1_2_8_9_1","unstructured":"European Medicines Agency (EMA) \u201cReal\u2010World Evidence | European Medicines Agency (EMA)\u201d(2022) https:\/\/www.ema.europa.eu\/en\/about\u2010us\/how\u2010we\u2010work\/data\u2010regulation\u2010big\u2010data\u2010other\u2010sources\/real\u2010world\u2010evidence."},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.202404\u2010439ED"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp\u20102023\u2010002033"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202108\u20101986OC"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.202102\u2010220RL"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/children10030554"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.16267"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.631527"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023\u2010022\u201002283\u2010z"},{"key":"e_1_2_8_18_1","unstructured":"Organization for Economic Co\u2010Operation and Development \u201cHealth at a Glance: Europe 2024\u201d(2024) https:\/\/doi.org\/10.1787\/b3704e14\u2010en."},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11030447"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)00585\u20102"},{"key":"e_1_2_8_21_1","unstructured":"World Health Organization \u201cProposal for the Addition of Ivacaftor\/Tezacaftor\/Elexacaftor to the WHO Model List of Essential Medicines for the Treatment of Adults and Children With Cystic Fibrosis\u201d(2024) https:\/\/cdn.who.int\/media\/docs\/default\u2010source\/2025\u2010eml\u2010expert\u2010committee\/addition\u2010of\u2010new\u2010medicines\/a.11_elexacaftor\u2010ivacaftor\u2010tezacaftor.pdf?sfvrsn=5133bfda_1."}],"container-title":["Pharmacology Research & Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/prp2.70138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T09:05:56Z","timestamp":1755075956000},"score":1,"resource":{"primary":{"URL":"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1002\/prp2.70138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,17]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/prp2.70138"],"URL":"https:\/\/doi.org\/10.1002\/prp2.70138","archive":["Portico"],"relation":{},"ISSN":["2052-1707","2052-1707"],"issn-type":[{"value":"2052-1707","type":"print"},{"value":"2052-1707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,17]]},"assertion":[{"value":"2025-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70138"}}