{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T19:33:30Z","timestamp":1787945610032,"version":"build-2784847793"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Res &amp; Perspec"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross\u2010sectional study on the addiction\u2010specific ward of the Department of Psychiatry, Social Psychiatry and Psychotherapy of Hannover Medical School, a large university hospital in northern Germany. The outcome measures were the nature and frequency of PIDPs compared with ADPs. Medication records of 1174 patients enrolled between January 2016 and December 2021 were reviewed. The median age of the study population (27.8% female) was 48\u2009years (interquartile range (IQR) 39\u201356). Patients took a median of 4 drugs (IQR 2\u20136). 12.8% of the study population were exposed to at least one PIDP (at least one grade\u20101 PIDP: 12.0%; at least one grade\u20102 PIDP: 1.3%; at least one grade\u20103 PIDP: 0.3%). Sedatives were the most common cause of grade\u20101 PIDPs, while grade\u20102 PIDPs were elicited predominantly by opioids. Nearly one third of the study population (29.0%) displayed at least one ADP. Physicians treating patients with substance use disorders should carefully monitor for PIDPs, particularly PIDPs elicited by sedatives and opioids. Addressing PIDPs may help prevent adverse drug reactions and reduce drug expenses.<\/jats:p>","DOI":"10.1002\/prp2.70211","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:17:38Z","timestamp":1766038658000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Duplicate Prescription Patterns in Patients With Substance Use Disorders"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5382-3014","authenticated-orcid":false,"given":"Johannes","family":"Heck","sequence":"first","affiliation":[{"name":"Institute for Clinical Pharmacology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5899-0113","authenticated-orcid":false,"given":"Benjamin","family":"Krichevsky","sequence":"additional","affiliation":[{"name":"Institute for General Practice and Palliative Care Hannover Medical School  Hannover Germany"},{"name":"Interdisciplinary Emergency Department University Hospital Schleswig\u2010Holstein, Campus Kiel  Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3262-8137","authenticated-orcid":false,"given":"Martin","family":"Schulze Westhoff","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2953-0166","authenticated-orcid":false,"given":"Konstantin Fritz","family":"Jendretzky","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3054-9905","authenticated-orcid":false,"given":"Martin","family":"Klietz","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0638-8571","authenticated-orcid":false,"given":"Stephan","family":"Greten","sequence":"additional","affiliation":[{"name":"Department of Neurology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5343-5280","authenticated-orcid":false,"given":"Alexander","family":"Glahn","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5004-3824","authenticated-orcid":false,"given":"Stefan","family":"Bleich","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0905-274X","authenticated-orcid":false,"given":"Sebastian","family":"Schr\u00f6der","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Social Psychiatry and Psychotherapy Hannover Medical School  Hannover Germany"},{"name":"PRACTIS Clinician Scientist Program, Dean's Office for Academic Career Development Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13167"},{"issue":"1","key":"e_1_2_9_3_1","first-page":"40","article-title":"Alcohol and Medication Interactions","volume":"23","author":"Weathermon R.","year":"1999","journal-title":"Alcohol Research & Health"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.191097"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2011.03605.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14703"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.35946\/arcr.v40.1.01"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1521-0391.2011.00140.x"},{"issue":"1","key":"e_1_2_9_9_1","article-title":"Pharmacotherapy for Anxiety and Comorbid Alcohol Use Disorders","volume":"1","author":"Ipser J. 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