{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:35:22Z","timestamp":1788435322473,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T00:00:00Z","timestamp":1610841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bpspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pharmacology Res &amp; Perspec"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cardiac rehabilitation program is well\u2010established but the Rehabilitation After Myocardial Infarction Trial (RAMIT) is reported that it does not affect mortality and morbidity of patients after myocardial infarction during follow\u2010up period. The objectives of the study were to compare functional walking capacity, risk factor control, and morbidities in follow\u2010up for cardiac rehabilitation (exercise + education), exercise only, and usual care among patients with coronary artery disease. A total of 492 male and female patients (age range: 45\u201373\u00a0years) with coronary artery disease after myocardial infarction or underwent percutaneous coronary intervention or coronary artery bypass grafting surgeries referred to cardiac rehabilitation were included in the study. Patients were participating in a cardiac rehabilitation program (exercise + education, CRP cohort, n\u00a0=\u00a0125), exercise only (USC cohort, n\u00a0=\u00a0182), or usual care (NCR cohort, n\u00a0=\u00a0185). Data regarding incremental shuttle walk test, lipid profile, the Patient Health Questionnaire 9, and morbidities in follow\u2010up of patients were retrospectively collected and analyzed. After completion of 1\u00a0year, cardiac rehabilitation program (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001, <jats:italic>q<\/jats:italic>\u00a0=\u00a020.939) and exercise (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001, <jats:italic>q<\/jats:italic>\u00a0=\u00a06.059) were successfully increased incremental shuttle walk test. After completion of 1\u00a0year, cardiac rehabilitation program reduced low\u2010density lipoprotein (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.007, <jats:italic>q<\/jats:italic>\u00a0=\u00a03.349) and depressive symptoms (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001, <jats:italic>q<\/jats:italic>\u00a0=\u00a05.649). Morbidities were reported fewer in the patients of CRP cohort than those of USC (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.003, <jats:italic>q<\/jats:italic>\u00a0=\u00a03.427) and NCR (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.003, <jats:italic>q<\/jats:italic>\u00a0=\u00a04.822) cohorts after completion of 1\u00a0year of program. Cardiac rehabilitation program (exercise +education) improved functional walking capacity, controlled risk factors, and reduced morbidities of patients with coronary artery disease than exercise only and usual care (Level of evidence: III).<\/jats:p>","DOI":"10.1002\/prp2.711","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T06:37:56Z","timestamp":1610951876000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of cardiac rehabilitation (exercise + education), exercise only, and usual care for patients with coronary artery disease: A non\u2010randomized retrospective analysis"],"prefix":"10.1002","volume":"9","author":[{"given":"Yanqun","family":"Hu","sequence":"first","affiliation":[{"name":"Healthcare Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taihao","family":"Wang","sequence":"additional","affiliation":[{"name":"Healthcare Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Healthcare Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Zhan","sequence":"additional","affiliation":[{"name":"Healthcare Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyan","family":"Han","sequence":"additional","affiliation":[{"name":"Healthcare Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3313-9896","authenticated-orcid":false,"given":"Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Neurology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Hainan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.011228"},{"key":"e_1_2_11_3_1","first-page":"267","article-title":"Chinese experts consensus on cardiac rehabilitation\/secondary prevention for coronary artery disease","volume":"41","author":"Chinese Society of Cardiology of Chinese Medical Association; Cardiovascular Committee of Chinese Association of Rehabilitation Medicine; Committee of Cardio\u2010Cerebral\u2010Vascular Diseases of Gerontological Society of China","year":"2013","journal-title":"Chin J Cardiovasc Dis"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005638"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487315569401"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487320905719"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-309209"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487313486040"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2014.11.014"},{"key":"e_1_2_11_10_1","first-page":"CD001800\u20101","article-title":"Exercise\u2010based cardiac rehabilitation for coronary heart disease","author":"Anderson L","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-036089"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-300302"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1474515117721129"},{"key":"e_1_2_11_14_1","first-page":"802","article-title":"Guidelines for Cardiovascular Rehabilitation and Secondary Prevention in China 2018 Simplified Edition","volume":"57","author":"Commitee of Cardiac Rehabilitation and Prevention of Chinese Association of Rehabilitation Medicine","year":"2018","journal-title":"Chin J Intern Med"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-016-0231-2"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2019.03.049"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S176639"},{"key":"e_1_2_11_18_1","first-page":"744","article-title":"Establishment and application of food frequency questionnaire method among Chinese","volume":"47","author":"Liu D","year":"2018","journal-title":"J Hyg Res"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.920900"},{"key":"e_1_2_11_20_1","first-page":"406","article-title":"Effects of comprehensive cardiac rehabilitation on functional capacity in a middle\u2010income country: A randomised controlled trial","volume":"105","author":"Chaves GS","year":"2019","journal-title":"Heart"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2011.05.005"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2017.07.002"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2017.03.001"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-301728"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0000000000000395"}],"container-title":["Pharmacology Research &amp; 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