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Research over the past two decades has led to a vastly improved understanding of the cellular and molecular mechanisms in the cochlea that lead to hearing deficits and the advent of novel strategies to combat them. Combined with innovative methods that enable local drug delivery to the inner ear, these insights have paved the way for promising therapies that are now under clinical investigation. 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San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrice","family":"Piu","sequence":"additional","affiliation":[{"name":"Otonomy, Inc.  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