{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T19:59:22Z","timestamp":1789415962965,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,9,10]],"date-time":"2008-09-10T00:00:00Z","timestamp":1221004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2009,1]]},"abstract":"Abstract<\/jats:title>\n \n BACKGROUND:<\/jats:bold>\n A dichloromethane\u2010methanol extract of the seeds of\n Piper tuberculatum<\/jats:italic>\n Jacq. (Piperaceae) and two isobutyl amides, 4,5\u2010dihydropiperlonguminine (1) and pellitorine (2), which were isolated by chromatographic methods, were assayed for their lethality against the sugarcane borer\n Diatraea saccharalis<\/jats:italic>\n F. (Lepidoptera: Pyralidae).\n <\/jats:p>\n \n RESULTS:<\/jats:bold>\n Bioassays were carried out with fourth\u2010instar caterpillars through topical application of test solutions to the dorsal surface of the prothorax, and dose\u2013response correlations were determined. Significant insect mortalities were observed 24, 48 and 72 h after treatment at concentrations of \u2265 100 \u00b5g insect\n \u22121<\/jats:sup>\n . The LD\n 50<\/jats:sub>\n and LD\n 90<\/jats:sub>\n values for compound 1 were 92.83 and 176.50 \u00b5g insect\n \u22121<\/jats:sup>\n , and for compound 2 they were 91.19 and 184.56 \u00b5g insect\n \u22121<\/jats:sup>\n .\n <\/jats:p>\n \n CONCLUSION:<\/jats:bold>\n According to the LD\n 50<\/jats:sub>\n and LD\n 90<\/jats:sub>\n for compounds 1 and 2, it can be inferred that the values reflect an acute lethal response to both compounds, based on interaction(s) of the toxicants with a primary target or series of targets. Thus, the amides were demonstrated to have potential value in the control of the sugarcane borer. Copyright \u00a9 2008 Society of Chemical Industry\n <\/jats:p>","DOI":"10.1002\/ps.1643","type":"journal-article","created":{"date-parts":[[2008,9,10]],"date-time":"2008-09-10T11:18:18Z","timestamp":1221045498000},"page":"47-51","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Isobutyl amides\u2014potent compounds for controlling\n Diatraea saccharalis<\/i>"],"prefix":"10.1002","volume":"65","author":[{"given":"Hosana M","family":"Debonsi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afonso T","family":"Murata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9rgio A","family":"de 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