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In light of the continuing need for new tools to address an ever\u2010changing array of fungal, weed and insect pests, <jats:styled-content style=\"fixed-case\">NPs<\/jats:styled-content> continue to be a source of models and templates for the development of new pest control agents. Interestingly, an examination of the literature suggests that <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> models exist for many of the pest control agents that were discovered by other means, suggesting that, had circumstances been different, these <jats:styled-content style=\"fixed-case\">NPs<\/jats:styled-content> could have served as inspiration for the discovery of a great many more of today's pest control agents. Here, an attempt is made to answer questions regarding the existence of an <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> model for existing classes of pesticides and what is needed for the discovery of new <jats:styled-content style=\"fixed-case\">NPs<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> models for pest control agents. \u00a9 2014 Society of Chemical Industry<\/jats:bold><\/jats:p>","DOI":"10.1002\/ps.3744","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T08:17:56Z","timestamp":1390983476000},"page":"1169-1185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":257,"title":["Natural products for pest control: an analysis of their role, value and future"],"prefix":"10.1002","volume":"70","author":[{"given":"B Clifford","family":"Gerwick","sequence":"first","affiliation":[{"name":"Dow AgroSciences Discovery Research Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas C","family":"Sparks","sequence":"additional","affiliation":[{"name":"Dow AgroSciences Discovery Research Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1185383"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066428"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527644179.ch14"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527644179.ch1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1079\/9781845933531.0005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo2020303"},{"key":"e_1_2_8_8_1","first-page":"3","volume-title":"Natural Product Chemistry for Drug Discovery","author":"Newman DJ","year":"2010"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/np200906s"},{"key":"e_1_2_8_10_1","first-page":"311","volume-title":"Agrochemicals from Natural Products","author":"Godfrey CRA","year":"1995"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.01.046"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/np300024u"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/bk-2006-0927.ch001"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ddtec.2004.10.009"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar700157x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527644179.ch27"},{"key":"e_1_2_8_17_1","unstructured":"Crop Protection Actives. 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