{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:59:57Z","timestamp":1780581597240,"version":"3.54.1"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,1,24]],"date-time":"2002-01-24T00:00:00Z","timestamp":1011830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The main mode of herbicidal activity of 2\u2010hydroxy\u20103\u2010alkyl\u20101,4\u2010naphthoquinones is shown to be inhibition of photosystem II (PSII). The herbicidal and\n                    <jats:italic>in vitro<\/jats:italic>\n                    activities have been measured and correlated with their (Log)octanol\/water partition coefficients (Log\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>o\/w<\/jats:sub>\n                    ). The length of the 3\u2010\n                    <jats:italic>n<\/jats:italic>\n                    \u2010alkyl substituent for optimal activity differed between herbicidal and\n                    <jats:italic>in vitro<\/jats:italic>\n                    activity. The maximum\n                    <jats:italic>in vitro<\/jats:italic>\n                    activity was given by the nonyl to dodecyl homologues (Log\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>o\/w<\/jats:sub>\n                    between 6.54 and 8.12), whereas herbicidal activity peaked with the\n                    <jats:italic>n<\/jats:italic>\n                    \u2010hexyl compound (Log\n                    <jats:italic>K<\/jats:italic>\n                    <jats:sub>o\/w<\/jats:sub>\n                    \u2009=\u20094.95). The effect of chain branching was also investigated using isomeric pentyl analogues substituted at position 3. All exhibited similar levels of\n                    <jats:italic>in vitro<\/jats:italic>\n                    activities but herbicidal activities differed, albeit moderately, with the exception of one analogue that was much less phytotoxic. Other modes of action were also investigated using two representative compounds. They did not show any activity on photosystem I or mitochondrial complex I, or generate toxic oxygen radicals by redox cycling reactions. Only moderate activity was found against mitochondrial complex III from plants, in contrast to much higher corresponding activity using an insect enzyme.\n                  <\/jats:p>\n                  <jats:p>\u00a9 2002 Society of Chemical Industry<\/jats:p>","DOI":"10.1002\/ps.428","type":"journal-article","created":{"date-parts":[[2005,1,22]],"date-time":"2005-01-22T05:26:06Z","timestamp":1106371566000},"page":"234-242","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Herbicidal action of 2\u2010hydroxy\u20103\u2010alkyl\u20101,4\u2010naphthoquinones"],"prefix":"10.1002","volume":"58","author":[{"given":"Philip J","family":"Jewess","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Higgins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate J","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen R","family":"Moss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian B","family":"Boogaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhupinder P\u200aS","family":"Khambay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,1,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1128\/jb.107.2.528-534.1971","article-title":"Bactericidal action of 2\u2010hydroxy\u20103\u2010(cyclopropyl)\u20101,4\u2010naphthoquinone on Bacillus megaterium","volume":"107","author":"Olenick J G","year":"1971","journal-title":"J Bacteriol"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ps.2780170611"},{"key":"e_1_2_6_4_2","first-page":"1363","article-title":"Naphthoquinone antimalarials XXII. 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