{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:33:46Z","timestamp":1784043226747,"version":"3.55.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      Walnut bacterial blight, caused by\n                      <jats:italic>Xanthomonas arboricola<\/jats:italic>\n                      pv.\n                      <jats:italic>juglandis<\/jats:italic>\n                      (Xaj), leads to significant yield losses in walnut production, which is a key agricultural sector in Chile. Conventional control methods based on copper have limitations owing to environmental concerns, phytotoxicity, and bacterial resistance. Plant\u2010derived compounds such as polygodial offer a promising alternative as a result of their potent antibacterial properties. This study aimed to develop and evaluate the antimicrobial efficacy of nanoemulsions containing drimanic compounds, specifically polygodial (\n                      <jats:bold>1<\/jats:bold>\n                      ) and epi\u2010polygodial (\n                      <jats:bold>2<\/jats:bold>\n                      ), as a sustainable strategy to control Xaj.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Both polygodial (\n                      <jats:bold>1<\/jats:bold>\n                      ) and epi\u2010polygodial (\n                      <jats:bold>2<\/jats:bold>\n                      ) demonstrated significant antibacterial activity against Xaj strains\n                      <jats:italic>in vitro<\/jats:italic>\n                      and\n                      <jats:italic>in planta<\/jats:italic>\n                      . In assays with immature walnut fruits, the nanoemulsion with compound\n                      <jats:bold>1<\/jats:bold>\n                      at 125\u2009ppm reduced disease severity by 40%, an efficacy level intermediate between the negative control and the commercial chemical treatment (65% reduction). The nanoformulations effectively suppressed infections on leaves and shoots, and importantly, no phytotoxic effects were observed on either fruits or plants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Polygodial and epi\u2010polygodial are potent antibacterial agents against Xaj, making them excellent candidates for new biopesticides. This study successfully formulated these drimanic compounds into stable nanoemulsions that effectively control walnut bacterial blight without causing phytotoxicity. The development of these nanoformulations represents a significant advancement towards sustainable and effective disease management in the walnut industry, offering a viable alternative to conventional copper\u2010based bactericides. \u00a9 2025 Society of Chemical Industry.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ps.70367","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T11:07:23Z","timestamp":1763032043000},"page":"2300-2312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Antibacterial agents to control of pathogenic\n                    <scp>\n                      <i>Xanthomonas arboricola<\/i>\n                    <\/scp>\n                    pv.\n                    <scp>\n                      <i>juglandis<\/i>\n                    <\/scp>\n                    on walnut fruits and plants by polygodial derivatives 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Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8639-0078","authenticated-orcid":false,"given":"Diyanira","family":"Castillo\u2010Novales","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica y Medioambiente Universidad T\u00e9cnica Federico Santa Mar\u00eda  Vi\u00f1a del Mar Chile"},{"name":"Departamento de Qu\u00edmica Universidad T\u00e9cnica Federico Santa Mar\u00eda  Valpara\u00edso Chile"},{"name":"Escuela de Agronom\u00eda Pontificia Universidad Cat\u00f3lica de Valpara\u00edso  Quillota Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina Navarrete","family":"Molina","sequence":"additional","affiliation":[{"name":"Millennium Nucleus Bioproducts, Genomics and Environmental Microbiology (BioGEM)  Valpara\u00edso Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo","family":"Salinas","sequence":"additional","affiliation":[{"name":"Escuela de Agronom\u00eda Pontificia Universidad Cat\u00f3lica de Valpara\u00edso  Quillota Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximena","family":"Besoa\u00edn","sequence":"additional","affiliation":[{"name":"Escuela de Agronom\u00eda Pontificia Universidad Cat\u00f3lica de Valpara\u00edso  Quillota Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Villena","sequence":"additional","affiliation":[{"name":"Center of Interdisciplinary Biomedical and Engineering Research for Health (MEDING), Escuela de Medicina, Facultad de Medicina Universidad de Valpara\u00edso  Vi\u00f1a del Mar Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Espinoza\u2010Catal\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica Universidad T\u00e9cnica Federico Santa Mar\u00eda  Valpara\u00edso 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