{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:16:05Z","timestamp":1789006565977,"version":"build-2803163510"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Oropouche fever, caused by the arbovirus Oropouche virus (OROV; Peribunyaviridae:\n                    <jats:italic>Orthobunyavirus:Orthobunyavirus oropouche<\/jats:italic>\n                    ), has significantly increased in Brazil, with &gt;25\u2009000 confirmed cases during the 2023\u20132025 outbreak. Historically endemic to the Amazon region, OROV is now spreading beyond its traditional range. The vectorial dynamics of OROV transmission remain under scrutiny. Although\n                    <jats:italic>Culicoides paraensis<\/jats:italic>\n                    is identified as the primary urban vector, the role of\n                    <jats:italic>Culex quinquefasciatus<\/jats:italic>\n                    and other culicids is still under debate, as laboratory studies indicate limited vector competence. Entomological investigations highlight the challenges of detecting OROV in nature, with low virus isolation rates from biting midges and mosquitoes. Vertical transmission in mosquitoes suggests potential alternative mechanisms for virus maintenance. Recent outbreaks in the Extra\u2010Amazonian areas emphasize the importance of comprehensive vector studies to refine control strategies. This review synthesizes seven decades of research on OROV epidemiology and vector competence, identifying critical knowledge gaps, such as the definitive wild cycle vector, and we suggest a research agenda. Addressing these gaps is pivotal for preventing further geographical spread, reducing fatalities, and mitigating the public health impact of this emerging arbovirus. \u00a9 2025 The Author(s).\n                    <jats:italic>Pest Management Science<\/jats:italic>\n                    published by John Wiley &amp; Sons Ltd on behalf of Society of Chemical Industry.\n                  <\/jats:p>","DOI":"10.1002\/ps.70460","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T07:41:48Z","timestamp":1766648508000},"page":"2785-2793","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["What are the vector species of the Oropouche virus?"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0787-749X","authenticated-orcid":false,"given":"Const\u00e2ncia Fl\u00e1via Junqueira","family":"Ayres","sequence":"first","affiliation":[{"name":"Department of Entomology Aggeu Magalh\u00e3es Institute (IAM), Oswaldo Cruz Foundation (Fiocruz\/PE), Campus da UFPE  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Lais Sena","family":"do Nascimento","sequence":"additional","affiliation":[{"name":"Department of Arbovirology and Hemorrhagic Fevers  Ananindeua PA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele Barbosa","family":"de Almeida Medeiros","sequence":"additional","affiliation":[{"name":"Department of Entomology Aggeu Magalh\u00e3es Institute (IAM), Oswaldo Cruz Foundation (Fiocruz\/PE), Campus da UFPE  Recife Brazil"},{"name":"Department of Arbovirology and Hemorrhagic Fevers  Ananindeua PA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim Pinto","family":"Nunes Neto","sequence":"additional","affiliation":[{"name":"Department of Arbovirology and Hemorrhagic Fevers  Ananindeua PA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"ICTV. 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Ministry of Health Technical Note No. 117\/2024\u2010CGARB\/DEDT\/SVSA\/MS \u2014 Bras\u00edlia: Ministry of Health(2024).https:\/\/www.gov.br\/saude\/pt\u2010br\/centrais\u2010de\u2010conteudo\/publicacoes\/notas\u2010tecnicas\/2024\/nota\u2010tecnica\u2010n\u2010117\u20102024\u2010cgarb\u2010dedt\u2010svsa\u2010ms.pdf."},{"key":"e_1_2_11_8_1","volume-title":"Epidemiological Update\u2014Oropouche in the Region of the Americas","author":"Pan American Health Organization\/World Health Organization","year":"2025"},{"key":"e_1_2_11_9_1","first-page":"246","article-title":"Meningitis associated with Oropouche virus infections","volume":"24","author":"Pinheiro PF","year":"1982","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2502.181189"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-021-00987-9"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-024-04941-5"},{"key":"e_1_2_11_13_1","first-page":"2370","article-title":"Fatal Oropouche virus infections in nonendemic region, Brazil, 2024","volume":"13","author":"Bandeira AC","year":"2024","journal-title":"Emerg Infect Dis"},{"key":"e_1_2_11_14_1","volume-title":"Health confirms a fetal death due to Oropouche in Pernambuco","author":"Brazil. 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First detection of Oropouche virus inCulicoides insignisin the Ucayali region Peru: evidence of a possible new vectormedRxiv 2024.12.06.24318268https:\/\/doi.org\/10.1101\/2024.12.06.24318268.","DOI":"10.1101\/2024.12.06.24318268"},{"key":"e_1_2_11_47_1","unstructured":"Evandro Chagas Institute (IEC\/SVSA\/MS) Unpublished data presented by the National Arbovirus Reference Laboratory during webinar by RELDA and RELEVA 13 Mar 2025 (personal communication)."},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parepi.2025.e00423"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6800036"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-11337-8"},{"key":"e_1_2_11_51_1","first-page":"1208","article-title":"Culex quinquefasciatus density associated with socioenvironmental conditions in a municipality with indeterminate transmission of lymphatic filariasis in northeastern Brazil","volume":"32","author":"Xavier A","year":"2022","journal-title":"Int J Environ Health Res"},{"key":"e_1_2_11_52_1","first-page":"855","article-title":"In Brazil Culex quinquefasciatus is widely distributed throughout the country and is often abundant in and around human habitations","volume":"93","author":"Brito AC","year":"1998","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"e_1_2_11_53_1","volume-title":"Epidemiological Bulletin No. 14, Surveillance of Arboviroses, epidemiological weeks 52\/2024 to 14\/2025","author":"Secretaria Estadual de Sa\u00fade de Pernambuco (SES\u2010PE)","year":"2025"},{"key":"e_1_2_11_54_1","first-page":"575","volume-title":"Medicina tropical e infectologia na Amaz\u00f4nia","author":"Pinheiro FP","year":"2013"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-73820-y"}],"container-title":["Pest Management Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ps.70460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ps.70460","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ps.70460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:37:02Z","timestamp":1784680622000},"score":1,"resource":{"primary":{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/10.1002\/ps.70460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":54,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/ps.70460"],"URL":"https:\/\/doi.org\/10.1002\/ps.70460","archive":["Portico"],"relation":{},"ISSN":["1526-498X","1526-4998"],"issn-type":[{"value":"1526-498X","type":"print"},{"value":"1526-4998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,24]]},"assertion":[{"value":"2025-10-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}