{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:06:34Z","timestamp":1778911594880,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFE0214300"],"award-info":[{"award-number":["2024YFE0214300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Plant diseases threaten global agriculture. A series of 22 novel indole\u2010benzoxazole derivatives were synthesized to evaluate their antimicrobial potential against eight plant pathogenic fungi and three bacteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Several compounds exhibited potent antimicrobial activity. Specifically,\n                      <jats:bold>C12<\/jats:bold>\n                      showed high efficacy against\n                      <jats:italic>Phomopsis<\/jats:italic>\n                      sp. (EC\u2085\u2080\u2009=\u20095.1\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      <jats:italic>vs<\/jats:italic>\n                      azoxystrobin 44.7\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      ) and\n                      <jats:italic>Rhizoctonia solani<\/jats:italic>\n                      (EC\u2085\u2080\u2009=\u20097.9\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      <jats:italic>vs<\/jats:italic>\n                      17.3\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      ).\n                      <jats:bold>C4<\/jats:bold>\n                      strongly inhibited\n                      <jats:italic>Xanthomonas axonopodis<\/jats:italic>\n                      pv.\n                      <jats:italic>citri<\/jats:italic>\n                      (EC\u2085\u2080\u2009=\u20098.5\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      <jats:italic>vs<\/jats:italic>\n                      thiodiazole copper 73.3\u2009\u03bcg\u2009mL\n                      <jats:sup>\u22121<\/jats:sup>\n                      ).\n                      <jats:italic>In vivo<\/jats:italic>\n                      assays confirmed their superior curative and protective efficacy. Mechanistic studies revealed that\n                      <jats:bold>C12<\/jats:bold>\n                      acted by disrupting cell wall\/membrane integrity, while\n                      <jats:bold>C4<\/jats:bold>\n                      functioned by suppressing biofilm formation and reducing extracellular polysaccharide production.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      <jats:bold>C12<\/jats:bold>\n                      and\n                      <jats:bold>C4<\/jats:bold>\n                      demonstrate promising antimicrobial potential through distinct action mechanisms, providing valuable candidates for the development of new plant disease control agents. \u00a9 2026 Society of Chemical Industry.\n                    <\/jats:p>\n                  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