{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:26:39Z","timestamp":1792005999051,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:00:00Z","timestamp":1771632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:00:00Z","timestamp":1771632000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      Plant\u2010parasitic nematodes and phytopathogenic fungi severely threaten agricultural production, requiring highly efficient and safe novel pesticides. Herein, two series of tralopyril\u2010triphenylphosphonium derivatives were synthesized, and their nematicidal\/fungicidal activities and biological safety were systematically evaluated against\n                      <jats:italic>Caenorhabditis elegans<\/jats:italic>\n                      ,\n                      <jats:italic>Meloidogyne incognita<\/jats:italic>\n                      , and phytopathogenic fungi.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      All target compounds showed nematicidal activity against\n                      <jats:italic>C. elegans<\/jats:italic>\n                      , with 7\u2009g (LC\u2085\u2080\u2009=\u200929.52\u2009mg\/L) exhibiting a significantly lower LC\u2085\u2080 than fosthiazate (LC\u2085\u2080\u2009=\u200972.37\u2009mg\/L). In\n                      <jats:italic>M. incognita<\/jats:italic>\n                      pot assays under root\u2010drenching conditions,\n                      <jats:bold>5f<\/jats:bold>\n                      at 50\/100\u2009mg\/L achieved 63.33%\/76.67% control efficacy, outperforming cyclobutrifluram (61.11%\/72.22%). At 100\u2009mg\/L,\n                      <jats:bold>5f<\/jats:bold>\n                      showed protective efficacy against rapeseed\n                      <jats:italic>Sclerotinia<\/jats:italic>\n                      stem rot in a semi\u2010\n                      <jats:italic>in vivo<\/jats:italic>\n                      assay with a protection rate of 77.98%, which was comparable to that of fludioxonil (80.01%) at the same concentration; meanwhile,\n                      <jats:bold>5a<\/jats:bold>\n                      showed a protective efficacy of 72.00% against rice sheath blight in pot assays, demonstrating efficacy comparable to that of fludioxonil (75.11%). Seed safety assays detected that these high\u2010activity compounds caused no significant phytotoxicity in rice, rapeseed, and wheat seeds.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The tralopyril\u2010triphenylphosphonium derivatives synthesized in this study exhibit high nematicidal and fungicidal activities, holding potential for further development as novel agrochemicals. \u00a9 2026 Society of Chemical Industry.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ps.70682","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:51:16Z","timestamp":1771663876000},"page":"5815-5825","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Synthesis, nematicidal activity, fungicidal activity, and safety evaluation of tralopyril\u2010triphenylphosphonium derivatives"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9442-9939","authenticated-orcid":false,"given":"Yue","family":"Yan","sequence":"first","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YanKun","family":"Lu","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wu","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binglan","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongze","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihong","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Pesticides, College of Agriculture, Yangtze University  Jingzhou China"},{"name":"Hubei Engineering Research Center for Pest Forewarning and Management. School of Agriculture, Yangtze University  Jingzhou China"},{"name":"MARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co\u2010construction by Ministry and Province) School of Agriculture, Yangtze University  Jingzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-19-0463"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1364-3703.2003.00170.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/forestry\/cpv028"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0198728"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.6b02181"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.phyto.40.032602.130045"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.23.354"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707288"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7799(97)01068-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026615666150302105622"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.1999.00543.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c05784"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.2c05071"},{"key":"e_1_2_7_15_1","first-page":"340","article-title":"Design, synthesis and bioactivity of 2\u2010(tralopyril\u20101\u2010yl) ethyl carboxylic acid derivatives","volume":"25","author":"Zhou P","year":"2023","journal-title":"Chin J Pestic Sci"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c04945"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rechem.2025.102780"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.5455"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c07536"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c01322"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c06595"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.7481"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.6023\/cjoc202403019"},{"key":"e_1_2_7_24_1","first-page":"55","article-title":"Laboratory safety test of Cartap+Ethylicin 17% WP on soaking Rice seeds","volume":"12","author":"Li H","year":"2013","journal-title":"Mod Agrochemicals"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826079408013400"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/10807039.2015.1133242"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8485"},{"key":"e_1_2_7_28_1","unstructured":"TsikoliaM BernierU AgramonteN CoyM BecnelJandClarkG Correlation of lipophilicity with mosquito larvicidal and repellent activities of novel trifluoromethylphenyl amides [Meeting Abstract]. Center for Medical Agricultural and Veterinary Entomology Agricultural Research Service U.S. Department of AgricultureAvailable:https:\/\/www.ars.usda.gov\/research\/publications\/publication\/?seqNo115=301885(2014)."}],"container-title":["Pest Management Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ps.70682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ps.70682","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ps.70682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:07:40Z","timestamp":1778908060000},"score":1,"resource":{"primary":{"URL":"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/10.1002\/ps.70682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,21]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/ps.70682"],"URL":"https:\/\/doi.org\/10.1002\/ps.70682","archive":["Portico"],"relation":{},"ISSN":["1526-498X","1526-4998"],"issn-type":[{"value":"1526-498X","type":"print"},{"value":"1526-4998","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,21]]},"assertion":[{"value":"2025-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}