{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:22:10Z","timestamp":1790108530819,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Fendioxypyracil is a new protoporphyrinogen oxidase (PPO; HRAC Group 14)\u2010inhibiting herbicide developed to expand post\u2010emergence weed control options. The compound combines a pyridine\u2010based core with an aryloxy side chain, resulting in high biological activity. Physiological profiling and enzyme assays confirmed PPO inhibition as its mode of action, with strong inhibition of both PPO1 and PPO2 from\n                      <jats:italic>Amaranthus tuberculatus<\/jats:italic>\n                      and higher potency than saflufenacil, particularly against PPO2. Greenhouse and field studies demonstrated broad\u2010spectrum efficacy against major broadleaf and grass weeds at low use rates. These results indicate that fendioxypyracil represents a valuable new PPO inhibitor for integrated weed management.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Greenhouse evaluations demonstrated high efficacy of fendioxypyracil against key grass weeds, including wild oat (\n                      <jats:italic>Avena fatua<\/jats:italic>\n                      ), crabrass (\n                      <jats:italic>Digitaria Sanginalis<\/jats:italic>\n                      ), goosegrass (\n                      <jats:italic>Eleusina indica<\/jats:italic>\n                      ) and barnyard grass (\n                      <jats:italic>Echinochloa crus\u2010galli<\/jats:italic>\n                      ), as well as strong control of major broadleaf species. Physiological characterization and enzyme inhibition assays confirmed PPO as the primary site and mode of action, with IC\u2085\u2080 values lower than those of the commercial standard saflufenacil for both PPO isoforms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Fendioxypyracil represents a next\u2010generation PPO inhibitor with broad\u2010spectrum and systemic activity, offering a valuable new tool for integrated weed management. Its high biological activity and efficacy across multiple weed taxa supports its potential to enhance on\u2010farm weed control strategies and contributes to resistance management programs. \u00a9 2026 The Author(s).\n                      <jats:italic>Pest Management Science<\/jats:italic>\n                      published by John Wiley &amp; Sons Ltd on behalf of Society of Chemical Industry.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ps.70763","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T09:16:07Z","timestamp":1774689367000},"page":"6794-6807","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Fendioxypyracil, a new and systemic\n                    <scp>PPO<\/scp>\n                    \u2010inhibiting herbicide for X\u2010spectrum weed control"],"prefix":"10.1002","volume":"82","author":[{"given":"Tobias","family":"Seiser","sequence":"first","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7846-6722","authenticated-orcid":false,"given":"Aimone","family":"Porri","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4512-9508","authenticated-orcid":false,"given":"Philipp","family":"Johnen","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Zeyer","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Wahrheit","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Betz","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Breght","family":"Vandenberghe","sequence":"additional","affiliation":[{"name":"BASF Belgium  Technologiepark 101, Gent Oost\u2010Vlaanderen (VLG) 9052 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Asher","sequence":"additional","affiliation":[{"name":"BASF Corporation  26 Davis Drive, Research Triangle Park 27709\u20103528 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0236-9375","authenticated-orcid":false,"given":"Liliana Parra","family":"Rapado","sequence":"additional","affiliation":[{"name":"BASF SE  Speyererstr, 2 67117 Limburgerhof Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1614\/WS-D-13-00063.1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0043174500073239"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374367-1.00081-1"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1614\/WS-D-09-00004.1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pestbp.2018.08.010"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.7728"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/agronomy13061595"},{"key":"e_1_2_8_9_1","unstructured":"SeiserT WitschelM JohannesM MassaD Parra RapadoL AponteRet al. 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