{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:17:53Z","timestamp":1787962673079,"version":"build-2784847793"},"reference-count":150,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The sulfonamide moiety (\u2013SO\n                    <jats:sub>2<\/jats:sub>\n                    NH\u2013) is a structurally versatile motif in agrochemical discovery. It can engage in hydrogen bonding, modulate molecular polarity and acidity, and act as a bioisostere or linking fragment in ligand design. Inspired by the mechanism of sulfonamide antibiotics, researchers have developed a range of agrochemicals active against plant pathogens and weeds. However, the development of sulfonamide\u2010based agrochemicals has been unbalanced: commercial products are mainly concentrated in herbicides and some fungicides, whereas research on insecticides, antiviral and plant\u2010growth regulators remains largely at the greenhouse trial stage. In fungicide research, chesulfamide derivatives, triazole sulfonamide and sulfonamide\u2010bearing succinate dehydrogenase inhibitor candidates exhibit diverse molecular optimization strategies. Acetolactate synthase and protoporphyrinogen\n                    <jats:styled-content style=\"fixed-case\">IX<\/jats:styled-content>\n                    oxidase inhibitors clearly demonstrate that structural modification can modulate the weed control spectrum and crop selectivity; nevertheless, single\u2010target herbicides are constantly confronted with the challenge of weed resistance. In the insecticidal and antiviral fields, the sulfonamide group is commonly used as an activity\u2010modulating linker or recognition motif. Multiple studies have reported sulfonamide compounds targeting vacuolar\u2010type H\n                    <jats:sup>+<\/jats:sup>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">ATPase<\/jats:styled-content>\n                    , viral coat protein or plant defense pathways. Sulfonamide abscisic acid (\n                    <jats:styled-content style=\"fixed-case\">ABA<\/jats:styled-content>\n                    ) analogs further validate the utility of this motif in plant\u2010growth regulation and stress response research. This article systematically reviews sulfonamide compounds for their herbicidal, fungicidal, bactericidal, insecticidal and antiviral activities, and summarizes their roles as ABA functional analogs over the past 20\u2009years. Particular attention is given to representative scaffolds, structure\u2013activity relationship and proposed targets or mechanisms. \u00a9 2026 Society of Chemical Industry.\n                  <\/jats:p>","DOI":"10.1002\/ps.71156","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T04:17:13Z","timestamp":1784866633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Sulfonamide in agricultural pest management: past and recent prospects"],"prefix":"10.1002","author":[{"given":"Anjing","family":"Liao","sequence":"first","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WenYi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Yan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengxin","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0740-0280","authenticated-orcid":false,"given":"Jian","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals Guizhou University  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2025.141347","article-title":"Structural and computational insights into a benzene sulfonamide derivative: hirshfeld surface, energy framework, optical, nbo, electronic and biological properties","volume":"1330","author":"Kanagathara N","year":"2025","journal-title":"J Mol Struct"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"E202301859","DOI":"10.1002\/slct.202301859","article-title":"Recent progress in synthesis of 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