{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:37:48Z","timestamp":1787067468377,"version":"build-2736575974"},"reference-count":65,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Chemical products against fungi and oomycetes pose serious environmental issues. In the last decade, the use of less impacting active ingredients was encouraged to reduce chemical inputs in viticulture. In this study, the effect of different antifungal compounds on grapevine agronomic, physiological, and molecular responses in the vineyard was evaluated in addition to protection against powdery and downy mildews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      In 2\u2009years and in two\n                      <jats:italic>Vitis vinifera<\/jats:italic>\n                      cultivars (Nebbiolo and Arneis), a conventional crop protection approach, based on traditional fungicides (sulfur and copper), was compared to combined strategies. A well\u2010known resistance inducer (potassium phosphonate),\n                      <jats:italic>Bacillus pumilus<\/jats:italic>\n                      strain QST 2808 and calcium oxide, both active ingredients whose biological interaction with grapevine is poorly characterized, were applied in the combined strategies in association with chemical fungicides. Despite a genotype effect occurred, all treatments optimally controlled powdery and downy mildews, with minimal variations in physiological and molecular responses. Gas exchange, chlorophyll content and photosystem II efficiency increased in treated plants at the end of season, along with a slight improvement in the agronomic performances, and an activation of molecular defense processes linked to stilbene and jasmonate pathways.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      The disease control strategies based on potassium phosphonate,\n                      <jats:italic>Bacillus pumilus<\/jats:italic>\n                      strain QST 2808 or calcium oxide combined with traditional chemical compounds did not cause severe limitations in plant ecophysiology, grape quality, and productive yields. The combination of potassium phosphonate and calcium oxide with traditional fungicides can represent a valuable strategy for reducing copper and sulfur inputs in the vineyards, including those organically managed. \u00a9 2023 The Authors.\n                      <jats:italic>Pest Management Science<\/jats:italic>\n                      published by John Wiley &amp; Sons Ltd on behalf of Society of Chemical Industry.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ps.7660","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T23:05:51Z","timestamp":1689116751000},"page":"4569-4588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of fungicide application on physiological and molecular responses of grapevine (\n                    <i>Vitis vinifera<\/i>\n                    L.): a comparison between copper and sulfur fungicides applied alone and in combination with novel fungicides"],"prefix":"10.1002","volume":"79","author":[{"given":"Amedeo","family":"Moine","sequence":"first","affiliation":[{"name":"Institute for Sustainable Plant Protection National Research Council (IPSP\u2010CNR)  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Centre of competence for the innovation in the agro\u2010environmental sector (Agroinnova)  Grugliasco Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Monchiero","sequence":"additional","affiliation":[{"name":"ANT\u2010NET  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Gribaudo","sequence":"additional","affiliation":[{"name":"Institute for Sustainable Plant Protection National Research Council (IPSP\u2010CNR)  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria 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