{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:37:56Z","timestamp":1765370276167,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31872011"],"award-info":[{"award-number":["31872011"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["scijournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pest Management Science"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      Previously, the herbicidal activity of\n                      <jats:italic>N<\/jats:italic>\n                      \u2010benzyl\u20102\u2010methoxybenzamides was discovered during a random screening program in our laboratory. The chemicals resulted in bleaching effect of newly grown leaves by interfering with the biosynthesis of\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2010carotene in plant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      A total of 28 benzamides were synthesized and subjected for the evaluation of herbicidal activity. Structure\u2013activity relationship (SAR) showed that introducing propargyloxy group at 5\u2010position of benzoyl\u2010benzene ring and fluorine or methyl group at 3\u2010 or 4\u2010position of benzyl\u2010benzene ring is beneficial for the activity. Post\u2010emergence herbicidal activities of compounds\n                      <jats:bold>406<\/jats:bold>\n                      and\n                      <jats:bold>412<\/jats:bold>\n                      were comparable to those of mesotrione and diflufenican. Studies on MOA showed that\n                      <jats:bold>406<\/jats:bold>\n                      decreased the level of both\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2010carotene and plastoquinone (PQ) in treated plants. The bleaching effect in green alga caused by\n                      <jats:bold>406<\/jats:bold>\n                      could be reversed by supplying exogenous homogentisic acid (HGA), the precursor of plastoquinone.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>\n                      <jats:italic>N<\/jats:italic>\n                      \u2010benzyl\u20102\u2010methoxy\u20105\u2010propargyloxybenzoamides were discovered as new candidates for bleaching herbicides. Preliminary investigation on mechanism of action (MOA) showed that the title compounds might indirectly interfere with carotenoid biosynthesis by blocking the production of PQ. \u00a9 2023 Society of Chemical Industry.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ps.7708","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T01:44:53Z","timestamp":1691631893000},"page":"5087-5095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>N<\/i>\n                    \u2010benzyl\u20102\u2010methoxy\u20105\u2010propargyloxybenzoamides, a new type of bleaching herbicides targeting the biosynthesis pathway of plastoquinone"],"prefix":"10.1002","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0202-7966","authenticated-orcid":false,"given":"Shaopeng","family":"Wei","sequence":"first","affiliation":[{"name":"College of Plant Protection, Northwest A&amp;F University  Yangling China"},{"name":"Shaanxi Province Key Laboratory Research &amp; 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