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Using the Kleier model, all these acidic analogues were predicted to be moderately phloem\u2010mobile, especially the <jats:italic>N<\/jats:italic>\u2010substituted derivatives. One of these latter molecules, <jats:italic>N<\/jats:italic>\u2010carboxymethyl\u20103\u2010cyano\u20104\u2010(2,3\u2010dichlorophenyl)pyrrole, exhibited some fungicidal activity on the pathogenic fungus <jats:italic>Eutypa lata<\/jats:italic>, and was then tested as a phloem\u2010mobile pesticide in the <jats:italic>Ricinus<\/jats:italic> system. The compound was indeed mobile in the sieve tubes and was not degraded to fenpiclonil in the phloem sap under our experimental conditions. Its concentration in the sap was closely correlated to the percentage of the undissociated form of the molecule in the external medium, and was similar under acidic conditions (external pH 4.6\u20135.0) to that of the herbicide glyphosate. Copyright \u00a9 2004 Society of Chemical Industry<\/jats:p>","DOI":"10.1002\/ps.906","type":"journal-article","created":{"date-parts":[[2004,6,15]],"date-time":"2004-06-15T15:41:18Z","timestamp":1087314078000},"page":"1063-1072","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Synthesis and phloem mobility of acidic derivatives of the fungicide 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