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Antimicrobial peptides (AMPs), particularly those derived from arthropod venoms, have emerged as promising alternatives due to their unique ability to target conserved microbial structures and minimize resistance development. Among these, Lasioglossin\u2010III (LL\u2010III) stands out for its remarkable potency and versatility. LL\u2010III exhibits a broad spectrum of activity encompassing antibacterial, antifungal, and anticancer properties, attributed to its structural features that facilitate selective interactions with microbial and cancer cell membranes. Despite its promising therapeutic profile, comprehensive reviews focusing specifically on LL\u2010III remain scarce, with most existing literature addressing lasioglossins only in general terms. 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