{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:06:08Z","timestamp":1784203568128,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T00:00:00Z","timestamp":1783814400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ascpt.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["CPT Pharmacom &amp; Syst Pharma"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1002\/psp4.70297","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T04:17:36Z","timestamp":1783916256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Current State\u2010of\u2010the\u2010Art and Future Advancements of Model\u2010Based Meta\u2010Analysis"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1509-1526","authenticated-orcid":false,"given":"Phyllis","family":"Chan","sequence":"first","affiliation":[{"name":"Genentech, Inc.  South San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Simeoni","sequence":"additional","affiliation":[{"name":"GSK  Brentford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5221-9157","authenticated-orcid":false,"given":"Matthew L.","family":"Zierhut","sequence":"additional","affiliation":[{"name":"Certara USA, Inc.  Radnor Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Maringwa","sequence":"additional","affiliation":[{"name":"Janssen\u2010Cilag BV  Breda the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9649-169X","authenticated-orcid":false,"given":"Jonathan","family":"French","sequence":"additional","affiliation":[{"name":"Johnson &amp; Johnson  Spring House Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,12]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/ebmed\u20102016\u2010110401"},{"key":"e_1_2_4_3_1","unstructured":"\u201cICH Harmonised Guideline: General Principles for Model\u2010Informed Drug Development \u201d(2026) https:\/\/database.ich.org\/sites\/default\/files\/ICH_M15_Step4_Final_Guideline_2026_0129.pdf."},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2011.242"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.12299"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2012.69"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2022.103908"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.3298"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.3636"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095\u2010022\u201003201\u20105"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.6045"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70059"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70159"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70053"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70158"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.3290"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70150"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70207"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70013"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70133"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70164"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70197"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70196"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70106"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70034"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70145"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.70195"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/cts.12541"},{"key":"e_1_2_4_29_1","unstructured":"\u201cConsiderations With Respect to Future MIDD Related Guidelines: Output From ICH Model\u2010Informed Drug Development (MIDD) Discussion Group (DG) \u201d(2021) https:\/\/database.ich.org\/sites\/default\/files\/ICH_MIDD_Roadmap_2022_0503.pdf."},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2025.115553"},{"key":"e_1_2_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2024.115459"},{"key":"e_1_2_4_32_1","unstructured":"\u201cRe: Docket No. FDA\u20102024\u2010N\u20101592: Promoting Effective Drug Development: Identifying Opportunities and Priorities for the Food and Drug Administration's Office of Clinical Pharmacology \u201dhttps:\/\/downloads.regulations.gov\/FDA\u20102024\u2010N\u20101592\u20100016\/attachment_1.pdf."}],"container-title":["CPT: Pharmacometrics &amp; Systems Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/psp4.70297","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/psp4.70297","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/psp4.70297","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T11:25:03Z","timestamp":1784201103000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1002\/psp4.70297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/psp4.70297"],"URL":"https:\/\/doi.org\/10.1002\/psp4.70297","archive":["Portico"],"relation":{},"ISSN":["2163-8306","2163-8306"],"issn-type":[{"value":"2163-8306","type":"print"},{"value":"2163-8306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70297"}}