{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T21:18:41Z","timestamp":1770499121951,"version":"3.49.0"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,4,15]],"date-time":"2003-04-15T00:00:00Z","timestamp":1050364800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The antibiotic effect of the active ingredients in Meijer\u2122 medicated chest rub (eucalyptus oil, camphor and menthol) as well as the inactive ingredients (thymol, oil of turpentine, oil of nutmeg and oil of cedar leaf) were studied <jats:italic>in vitro<\/jats:italic> using the fungal pathogens responsible for onychomycosis, such as the dermatophytes <jats:italic>Tricophyton rubrum, Trichophyton mentagrophytes, Microsporum canis, Epidermophyton \ufb02occosum <\/jats:italic>and<jats:italic> Epidermophyton stockdale<\/jats:italic>. The zones of inhibition data revealed that camphor (1), menthol (2), thymol (3) and oil of <jats:italic>Eucalyptus citriodora<\/jats:italic> were the most ef\ufb01cacious components against the test organisms. The MIC<jats:sub>100<\/jats:sub> for mixtures of these four components in various carrier solvents revealed that formulations consisting of 5 mg\/mL concentrations of each have a potential to be efffective in controlling onychomycosis. Copyright \u00a9 2003 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.1164","type":"journal-article","created":{"date-parts":[[2003,4,25]],"date-time":"2003-04-25T13:26:04Z","timestamp":1051277164000},"page":"376-379","source":"Crossref","is-referenced-by-count":18,"title":["<i>In vitro<\/i> antagonistic activity of monoterpenes and their mixtures against \u2018toe nail fungus\u2019 pathogens"],"prefix":"10.1002","volume":"17","author":[{"given":"Russel S.","family":"Ramsewak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muraleedharan G.","family":"Nair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Stommel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Selanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,4,15]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70063-L"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/np50064a022"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf9805808"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/np970459f"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1093\/ajhp\/56.9.865","article-title":"Management of toenail onychomycosis","volume":"56","author":"Tom CM","year":"1999","journal-title":"Am J Health\u2010Syst Pharm"},{"key":"e_1_2_1_7_1","first-page":"513","article-title":"Diagnosing and treating onychomycosis","volume":"42","author":"Zaias N","year":"1996","journal-title":"J Fam Pract"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fptr.1164","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.1164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T18:50:26Z","timestamp":1700247026000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.1164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["10.1002\/ptr.1164"],"URL":"https:\/\/doi.org\/10.1002\/ptr.1164","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,4]]}}}