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Pentobarbital\u2010induced sleeping time was used to study the central depressant effect of the extract. The ethanolic extract caused a dose dependent inhibition of acetic acid\u2010induced abdominal writhing and leukocyte migration, and produced a significant, dose\u2010related increase in the duration of sleep. The results suggest that <jats:italic>Spiranthera odoratissima<\/jats:italic> roots contain compounds with anti\u2010inflammatory and central depressant actions. Copyright \u00a9 2004 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.1301","type":"journal-article","created":{"date-parts":[[2005,3,2]],"date-time":"2005-03-02T11:22:37Z","timestamp":1109762557000},"page":"963-966","source":"Crossref","is-referenced-by-count":8,"title":["Analgesic and anti\u2010inflammatory activity of the ethanolic extract from <i>Spiranthera odoratissima<\/i> A. St. Hillaire (Manac\u00e1) roots"],"prefix":"10.1002","volume":"18","author":[{"given":"L. 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